CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1776
Family Name Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-(5-chloro-6-methoxy-naphthalen-2-yl)-pyridine Family
No. of Seeds 2 No. of Other Members 5
Family Centroid CFAMM00250311 Functional Category Investigative Drug
Superfamily Cytochrome P450 11B1, mitochondrial and Aromatase Binder Superfamily 2
Class Class 1129

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Amyloid beta A4 protein Inhibitor Florbetapir F-18 Family 8 265
Nicotinic acetylcholine receptor Ligand AZD0328 Family 11 97
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Lig... 9 115
Reverse transcriptase Inhibitor 3'thiacytidine Family 4 29
Hemoglobin subunit alpha Inhibitor 2-[(2-methoxy-5-methylpheno... 5 48
Hemoglobin subunit alpha Inhibitor 4-[(5-methoxy-2-methylpheno... 3 12
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 5 23
Estradiol 17-beta-dehydrogenase 1 Inhibitor 4'-(6-methoxypyrid... 5 34
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 12 3
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 13 26
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 7 6
Oestrogen receptor and Estrogen receptor beta Ligand Estrogen ... 7 2
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 4 35
RAF proto-oncogene serine/threonine-protein kinase Inhibitor 5... 3 7
Cytochrome P450 11B1, mitochondrial Inhibitor 5-(6-methoxynaph... 7 4
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor 5-hexy... 4 5
Metabotropic glutamate receptor 5 Ligand 3-methoxy-5-(1,5-naph... 4 20
Urokinase-type plasminogen activator and Plasminogen inhibitor... 1 2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 3 1
Renin inhibitor AGN-PC-09M4GD family 3 4
Glucocorticoid receptor ligand SureCN3894124 family 3 0
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 2
Sodium/hydrogen exchanger 1 inhibitor 2-[(E)-[7-(2-chloropheny... 2 0
Cytochrome P450 11B2, mitochondrial and Steroid 17-alpha-hydro... 1 0
Urokinase-type plasminogen activator and Plasminogen inhibitor... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00250310 DNC005723 Investigative Drug 3-(1-Chloro-7-methoxy-naphthalen-2-yl)-pyridine
CFAMM00250311 DNC005720 Investigative Drug 3-(5-Chloro-6-methoxy-naphthalen-2-yl)-pyridine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26413 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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