CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1779
Family Name Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 1-(3-methoxy-naphthalen-2-yl)-1h-imidazole Family
No. of Seeds 2 No. of Other Members 9
Family Centroid CFAMM00250354 Functional Category Investigative Drug
Superfamily Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 1-(3-methoxy-naphthalen-2-yl)-1h-imidazole Superfamily
Class Class 2246

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Astemizole Family 7 240
Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-[3-(4-... 7 128
Aromatase Inhibitor 4-((1h-imidazol-1-yl)methyl)-2h-chromen-2-... 3 69
Cytochrome P450 3A4 Inhibitor SK&F-96365 Family 2 26
Steroid 17-alpha-hydroxylase/17,20 lyase Inhibitor Rac-4'-(1-i... 5 9
Protein farnesyltransferase subunit beta Inhibitor A-313326 Fa... 85 149
Potassium voltage-gated channel subfamily H member 2 Ligand (1... 64 70
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 9 19
DNA-(apurinic or apyrimidinic site) lyase and Retinal dehydrog... 1 3
Aromatase inhibitor AGN-PC-075MOK family 1 4
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 5 4
Cytochrome P450 26A1 inhibitor SureCN4280032 family 1 1
Cytochrome P450 26A1 and Cytochrome P450 3A4 inhibitor 3-[6-[(... 14 26
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 7 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 6
Corticotropin-releasing factor receptor 1 and Corticotropin-re... 3 14
Histamine H3 receptor and Sodium-dependent serotonin transport... 2 0
Leukotriene A-4 hydrolase inhibitor AGN-PC-00EW8S family 1 2
Aromatase inhibitor 4-[(Z)-1-(3,5-dimethoxyphenyl)-3-imidazol-... 1 2
Delta-type opioid receptor and Kappa-type opioid receptor liga... 2 0
Alpha-1A adrenergic receptor ligand AGN-PC-0793UT family 3 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00250354 DNC005727 Investigative Drug 1-(3-Methoxy-naphthalen-2-yl)-1H-imidazole
CFAMM00250353 DNC005732 Investigative Drug 1-(6-Methoxy-naphthalen-2-yl)-1H-imidazole

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27518 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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