CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Peptide deformylase, mitochondrial Inhibitor BB-3497 Family
No. of Seeds 7 No. of Other Members 68
Family Centroid CFAMM00183331 Functional Category Investigative Drug
Superfamily Peptide deformylase, mitochondrial Inhibitor BB-3497 Superfamily
Class Class 1449

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Actinonin Family 2 12
Chymase Inhibitor Bceab Family 5 22
Interstitial collagenase Inhibitor Ro-31-4724 Family 2 10
Disintegrin and metalloproteinase domain-containing protein 17... 2 0
Peptide deformylase inhibitor (2S)-N-acetyl-1-[(2R)-2-(cyclope... 9 0
Interstitial collagenase and Stromelysin-1 inhibitor tert-buty... 2 8
Matrix metalloproteinase-9 and Interstitial collagenase inhibi... 1 0
Peptide deformylase inhibitor ethyl 1-[(2S)-2-[[(2R)-2-[[formy... 1 0
72 kDa type IV collagenase and Interstitial collagenase inhibi... 1 1
Interstitial collagenase and 72 kDa type IV collagenase inhibi... 1 0
Peptide deformylase inhibitor (2S)-2-(cyclohexylcarbamoylamino... 3 0
Histone deacetylase and Histone deacetylase 3 inhibitor (3S,6S... 1 0


External ID

Functional Category

Molecule Name

CFAMM00183293 CHEMBL122067 Bioactive (2R)-2-butyl-N-[(2S)-1-(dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-N'-hydroxybutanediamide
CFAMM00183284 CHEMBL84969 Bioactive N-[(2S)-1-(dimethylamino)-3,3-dimethyl-1-oxobutan-2-yl]-2-[[formyl(hydroxy)amino]methyl]hexanamide
CFAMM00183295 CHEMBL144857 Bioactive (2R,3S)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N'-hydroxy-2-(2-methylpropyl)-3-pyrrolidin-1-ylbutanediamide
CFAMM00183313 CHEMBL439944 Bioactive (2R,3R)-N-[(2R)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N'-hydroxy-3-methyl-2-(2-methylpropyl)butanediamide
CFAMM00183318 DNC003950 Investigative Drug RO-319790
CFAMM00183339 DNC004067 Investigative Drug Ro-37-9790
CFAMM00183331 DNC000283 Investigative Drug BB-3497

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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