CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1781
Family Name Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-[2-(3-phenyl-ureido)-ethyl]-benzenesulfonamide Family
No. of Seeds 5 No. of Other Members 72
Family Centroid CFAMM00250380 Functional Category Investigative Drug
Superfamily Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-[2-(3-phenyl-ureido)-ethyl]-benzenesulfonamide Superfamily
Class Class 1554

Cousin Family NamesSeedsMembers
Sodium channel Ligand iminostilbene derivative (tricyclic stru... 2 46
Dihydropterin pyrophosphokinase-dihydropteroate synthase Inhib... 9 88
Mannose-6-phosphate isomerase Inhibitor Sulfacetamide Family 19 117
5-hydroxytryptamine receptor 1A and Sigma non-opioid intracell... 7 28
Urokinase-type plasminogen activator Inhibitor N-(1-adamantyl)... 2 15
Bifunctional epoxide hydrolase 2 Inhibitor 1-cyclohexyl-3-phen... 5 65
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor N-(4-s... 12 92
Potassium voltage-gated channel subfamily A member 5 Ligand N-... 8 32
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 14 78
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 2-morp... 6 81
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 3-(3-p... 7 17
Androgen receptor Ligand YM-175735 Family 30 129
5-hydroxytryptamine receptor 6 Ligand N-(3-(2-aminoethyl)pheny... 8 25
Kinesin-like protein KIF11 Inhibitor N-{4'-[(trifluoromethyl)s... 3 1
Kinesin-like protein KIF11 Inhibitor N-(4'-bromo-3,3'-difluoro... 2 0
Kinesin-like protein KIF11 Inhibitor N-[4'-(trifluoromethyl)-4... 7 134
Fructose-1,6-bisphosphatase 1 Inhibitor 1-(4-aminophenylsulfon... 2 1
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 2 2
DNA topoisomerase Inhibitor 6-(naphthalen-2-ylamino)-1h-pyrimi... 2 1
Growth hormone secretagogue receptor type 1 ligand AGN-PC-07ZB... 2 2
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-04TFLH family 6 11
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-04TGG7 family 2 3
Carbonic anhydrase 9 and Carbonic anhydrase 12 inhibitor 3n2p ... 1 0
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor 1-(2-c... 1 1
Bifunctional epoxide hydrolase 2 inhibitor 1-(2,4-dimethylphen... 4 8
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-[[4... 7 11
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor 1-(3,5... 2 0
Carbonic anhydrase 1 and Carbonic anhydrase 13 inhibitor 4-(be... 1 0
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor 1-(3,4... 1 0
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor 1-(1-$... 1 7
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 3 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 2
C-C chemokine receptor type 5 ligand AC1L9YPM family 3 6
Carbonic anhydrase and Carbonic anhydrase 2 inhibitor AGN-PC-0... 2 0
Sterol O-acyltransferase 1 inhibitor SureCN7565101 family 2 10
Acyl-CoA:cholesterol acyltransferase inhibitor 1-[2,6-di(propa... 7 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00250391 CHEMBL1643306 Bioactive T6752501
CFAMM00250397 CHEMBL1615280 Bioactive 3n3j
CFAMM00250447 CHEMBL78755 Bioactive 1-(4-methylphenyl)sulfonyl-3-(4-sulfamoylphenyl)urea
CFAMM00250399 DNC011353 Investigative Drug GNF-PF-2893
CFAMM00250380 DNC005758 Investigative Drug 4-[2-(3-Phenyl-ureido)-ethyl]-benzenesulfonamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

42616 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543