CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1790
Family Name Melanin-concentrating hormone receptor 1 Ligand Gnf-pf-2322 Family
No. of Seeds 3 No. of Other Members 95
Family Centroid CFAMM00250615 Functional Category Investigative Drug
Superfamily Sodium-dependent serotonin transporter and Melanin-concentrating hormone receptor 1 Binder Superfamily
Class Class 918

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase Chk1 and Serine/threonine-prot... 23 121
Receptor tyrosine-protein kinase erbB-2 Inhibitor CP-724714 Fa... 4 180
D(3) dopamine receptor Ligand PF-217830 Family 21 7
Smoothened homolog Inhibitor LDE225 Family 3 76
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
Peptide deformylase, mitochondrial Inhibitor 5-(4-methoxypheno... 5 61
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 3 64
Adenosine receptor A1 and Adenosine receptor A3 Ligand 4-metho... 1 16
Melanin-concentrating hormone receptor 1 Ligand 8-sec-butoxy-q... 30 39
D(2) dopamine receptor Ligand SLV-314 Family 19 69
Melanin-concentrating hormone receptor 1 Ligand ADS-102891 Family 6 51
Melanin-concentrating hormone receptor 1 Ligand ADS-103214 Family 3 4
C-X-C chemokine receptor type 3 Ligand AMG-487 Family 28 73
Reverse transcriptase Inhibitor Atevirdine Family 4 55
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 17 49
Sodium channel protein type 5 subunit alpha Ligand Enecadin Fa... 1 11
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 6 35
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 5 25
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 3
Epidermal growth factor receptor ligand N-[4-(3-chloro-4-fluor... 6 47
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN12658... 3 19
Prostaglandin D2 receptor ligand 3-[2-methoxy-6-[2-(4-methoxyp... 2 12
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL13704... 1 7
Methionine--tRNA ligase inhibitor 2-[3-[(2-ethoxy-5-iodo-3-met... 9 32
Tyrosine-protein kinase JAK2 inhibitor 5-(3-methoxyphenyl)-N-[... 2 11
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 3 21
Prostaglandin D2 receptor ligand 2-[3-[2-methoxy-6-[2-(4-metho... 4 12
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 1 0
Adenosine receptor A1 and Adenosine receptor A3 ligand AGN-PC-... 6 8
Cholecystokinin receptor type A ligand AGN-PC-0A9ULH family 8 8
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic ... 5 12
Corticotropin-releasing factor receptor 1 ligand 6-ethyl-3-met... 6 10
Dihydrofolate reductase inhibitor 7-(3,4-dimethoxyphenyl)-6-me... 1 3
Dihydrofolate reductase inhibitor 3-(2,4-diamino-6-methylquina... 2 1
Dihydrofolate reductase inhibitor 7-(2-ethoxynaphthalen-1-yl)-... 3 2
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 16 19
Histamine H4 receptor and Histamine H3 receptor ligand 7-(fura... 2 2
5-hydroxytryptamine receptor 1B and Alpha-2A adrenergic recept... 1 0
Melanin-concentrating hormone receptor 1 ligand (E)-N-[2-[4-(1... 1 1
Smoothened homolog and Mitogen-activated protein kinase 14 inh... 7 11
Microsomal triglyceride transfer protein large subunit inhibit... 9 0
Acetylcholinesterase and Butyrylcholinesterase inhibitor (E)-3... 4 5
Cholinesterase and Acetylcholinesterase inhibitor 6-[2-methoxy... 12 6
Angiopoietin-1 receptor and Vascular endothelial growth factor... 4 6
Receptor tyrosine-protein kinase erbB-2 ligand SureCN4461871 f... 2 2
TRAF2 and NCK-interacting protein kinase inhibitor 4-methoxy-3... 4 1
Motilin receptor ligand SureCN2765637 family 1 1
Renin and Cytochrome P450 3A4 inhibitor AGN-PC-046RG9 family 8 28
Epidermal growth factor receptor ligand SureCN2989664 family 5 2
Bifunctional dihydrofolate reductase-thymidylate synthase inhi... 2 6
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 3 10
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 18 0
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 18 0
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 3 1
Acyl-CoA desaturase inhibitor SureCN1182546 family 2 5
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 5 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 4 3
Melanin-concentrating hormone receptor 1 ligand (E)-N-[2-(4-cy... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00250620 CHEMBL184084 Bioactive AGN-PC-00AL3S
CFAMM00250616 DNC005784 Investigative Drug GNF-PF-1550
CFAMM00250615 DNC005783 Investigative Drug GNF-PF-2322

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

24347 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543