CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1793
Family Name Cholecystokinin receptor type A Ligand L-708474 Family
No. of Seeds 14 No. of Other Members 82
Family Centroid CFAMM00250779 Functional Category Investigative Drug
Superfamily Cholecystokinin receptor type A Ligand L-708474 Superfamily
Class Class 1656

Cousin Family NamesSeedsMembers
Benzodiazepine receptor ligand benzodiazepine derivative Fludi... 11 78
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Benzodiazepine receptor Ligand Clorazepate Family 2 3
Gamma-aminobutyric acid receptor ligand benzodiazepine derivat... 2 8
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 10 157
Benzodiazepine receptor ligand benzodiazepine derivative Fluni... 2 22
Transient receptor potential cation channel subfamily V member... 15 158
Motilin receptor Ligand GSK962040 Family 30 457
Amg 423 family 7 47
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 19 186
5-hydroxytryptamine receptor 2B Ligand Sb 206553 Family 14 21
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 9 19
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
Androgen receptor Ligand YM-175735 Family 30 129
Cannabinoid receptor 1 Ligand 1,3,5-triphenylimidazolidine-2,4... 2 17
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 12 4
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Protein farnesyltransferase subunit beta and Protein farnesylt... 3 5
Substance-P receptor ligand (2S)-2-N-[(2S)-1-[benzyl(methyl)am... 2 2
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 5 2
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 14 8
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 7 5
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 15 12
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 4 0
Lethal factor inhibitor (2R)-2-(4-fluoro-3,5-dimethylanilino)-... 11 8
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 7 20
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 1 2
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 3 3
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 2 0
Substance-P receptor ligand (2S,4S)-2-N-[3-(diethylamino)propy... 2 7
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 8 1
Smoothened homolog inhibitor (8aS)-N-[2-(3-cyanophenyl)pyridin... 3 4
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 6 0
Baculoviral IAP repeat-containing protein 2 and E3 ubiquitin-p... 2 1
Furin inhibitor N-[(2S)-1-[[(2S)-1-[[(2S)-1-(4-carbamimidoylan... 3 16
Gastrin/cholecystokinin type B receptor ligand 3-[3-[[2-[5-cyc... 7 2
Nociceptin receptor ligand 2-[3-[1-[(1R)-1,2-dihydroacenaphthy... 2 0
Microsomal triglyceride transfer protein large subunit inhibit... 8 1
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 6 13
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 4 0
Gastrin/cholecystokinin type B receptor ligand 2-[5-cyclohexyl... 2 1
Sodium channel protein type 9 subunit alpha ligand tert-butyl ... 2 30
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 4 4
Oxytocin receptor ligand N-[1-[2-[[(2S)-1-amino-3-(3,4-dichlor... 1 0
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 4 0
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 7 12
Substance-P receptor ligand N-[[3,5-bis(trifluoromethyl)phenyl... 1 0
Growth hormone secretagogue receptor type 1 ligand SureCN77944... 1 2
Gastrin/cholecystokinin type B receptor ligand AGN-PC-01ZDS6 f... 6 0
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 11 4
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 2 5
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 1 1
Coagulation factor VII and Prothrombin inhibitor 2-[(4-carbami... 1 2
Coagulation factor VII and Prothrombin inhibitor 2-[(4-carbami... 2 1
Coagulation factor VII inhibitor AGN-PC-0752PN family 1 1
Coagulation factor VII and Prothrombin inhibitor AGN-PC-0752NM... 2 3
Gastrin/cholecystokinin type B receptor ligand 2-[5-cyclohexyl... 1 1
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 1 0
Putative NP ZINC55466512 Family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00250728 CHEMBL153308 Bioactive SureCN1574327
CFAMM00250785 CHEMBL545122 Bioactive 1-[(3R)-5-(3-azabicyclo[3.2.2]nonan-3-yl)-1-methyl-2-oxo-3H-1,4-benzodiazepin-3-yl]-3-(3-methylphenyl)urea;hydrochloride
CFAMM00250807 CHEMBL349291 Bioactive SureCN5198570
CFAMM00250776 CHEMBL2067982 Bioactive 1-[(3R)-1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]-3-[3-(tritritiomethyl)phenyl]urea
CFAMM00250742 CHEMBL540596 Bioactive 1-[(3S)-5-(3-azabicyclo[3.2.2]nonan-3-yl)-1-methyl-2-oxo-3H-1,4-benzodiazepin-3-yl]-3-(3-methylphenyl)urea;hydrochloride
CFAMM00250779 DNC014546 Investigative Drug L-708474
CFAMM00250752 DNC014562 Investigative Drug L-740093
CFAMM00250724 DNC014745 Investigative Drug FR-175985
CFAMM00250781 DNC005790 Investigative Drug L-365260

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27284 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543