CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1831
Family Name Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Phenyldifluoromethanesulfonamide Family
No. of Seeds 3 No. of Other Members 25
Family Centroid CFAMM00251736 Functional Category Investigative Drug
Superfamily Carbonic anhydrase 1 and Carbonic anhydrase 2 Binder Superfamily 12
Class Class 1935

Cousin Family NamesSeedsMembers
Prothrombin Inhibitor 4-tert-butylbenzenesulfonic Acid Family 1 39
Carbonic anhydrase 2 Inhibitor 4-flourobenzenesulfonamide Family 4 16
Carbonic anhydrase 2 Inhibitor Indane-5-sulfonamide Family 1 7
Carbonic anhydrase 2 Inhibitor 4-(2-aminoethyl)benzenesulfonam... 3 30
Carbonic anhydrase 2 and Carbonic anhydrase 9 Inhibitor P-TOLU... 5 27
Kinesin-like protein KIF11 Inhibitor 4'-(trifluoromethyl)-4-bi... 10 8
Indoleamine 2,3-dioxygenase 1 Inhibitor Benzenemethanethiol Fa... 3 30
Cysteine protease Inhibitor S-benzyl Phenylmethanesulfinothioa... 1 5
Carbonic anhydrase 9 and Carbonic anhydrase 1 inhibitor 3-[2-(... 2 0
Prothrombin and Trypsin-1 inhibitor methyl N'-benzylsulfonylca... 1 0


External ID

Functional Category

Molecule Name

CFAMM00251718 DNC005930 Investigative Drug 4-methylphenyl-difluoromethanesulfonamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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