CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID185
Family Name Reverse transcriptase Inhibitor Benzothiadiazines Family
No. of Seeds 4 No. of Other Members 21
Family Centroid CFAMM00183401 Functional Category Investigative Drug
Superfamily Reverse transcriptase Inhibitor Benzothiadiazines Superfamily
Class Class 853

Cousin Family NamesSeedsMembers
Dihydropterin pyrophosphokinase-dihydropteroate synthase inhib... 5 60
Metabotropic glutamate receptor 5 Ligand ADX-48621 Family 15 444
Adenosine receptor A3 and Dual specificity mitogen-activated p... 5 27
Potassium voltage-gated channel subfamily H member 2 Ligand AZ... 21 42
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 10 3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 27
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 0
Cyclin-dependent kinase 1 inhibitor 4-[[4-(3H-benzimidazol-5-y... 1 0
Aurora kinase B and Vascular endothelial growth factor recepto... 1 2
Cyclin-dependent kinase 2 inhibitor Imidazo[1,2-a]pyridine der... 4 0
Cyclin-dependent kinase 2 inhibitor Imidazo[1,2-b]pyridazine d... 2 1
Prostaglandin D2 receptor 2 ligand SureCN2516080 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00183408 CHEMBL2111765 Bioactive ethyl 5-[(Z)-[[3-[[[4-[(2-methylimidazo[4,5-c]pyridin-1-yl)methyl]phenyl]sulfonylamino]methyl]phenyl]-pyridin-3-ylmethylidene]amino]oxypentanoate
CFAMM00183404 CHEMBL117018 Bioactive ethyl 5-[(E)-[[3-[[[4-[(2-methylimidazo[4,5-c]pyridin-1-yl)methyl]phenyl]sulfonylamino]methyl]phenyl]-pyridin-3-ylmethylidene]amino]oxypentanoate
CFAMM00183412 CHEMBL157078 Bioactive SureCN7851331
CFAMM00183401 DNC000300 Investigative Drug Benzothiadiazines

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26821 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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