CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1854
Family Name Arachidonate 15-lipoxygenase Inhibitor Hydrohalisulfate 1 Family
No. of Seeds 6 No. of Other Members 6
Family Centroid CFAMM00252207 Functional Category Investigative Drug with Human Metabolite & Natural Product
Superfamily Tyrosinase and Arachidonate 15-lipoxygenase Binder Superfamily
Class Class 2231

Cousin Family NamesSeedsMembers
Cannabinoid receptor 1 Ligand Marinol Family 32 454
Oestrogen receptor ligand steroid Estradiol derivative Fulvest... 3 64
Fatty-acid amide hydrolase 1 Inhibitor Propofol Family 5 428
Estrogen receptor beta Ligand Conjugated Estrogens Family 12 210
Oestrogen receptor ligand steroid Estradiol Family 18 147
Oestrogen receptor ligand Dienestrol Family 35 440
Oestrogen receptor Ligand Mestranol Family 2 29
Noradrenergic re-uptake and Opioid receptor Ligand Tapentadol ... 21 79
Sphingosine kinase 2 Inhibitor Phenoxodiol Family 24 682
NAD-dependent protein deacetylase sirtuin-1 Inhibitor SRT501 F... 19 88
TS-071 family 8 36
Bile acid receptor Ligand SR-45023A (apomine) Family 3 34
Estrogen receptor beta Ligand 1-chloro-6-(4-hydroxyphenyl)-2-n... 12 23
Oestrogen receptor and Estrogen receptor beta Ligand 6-(4-hydr... 30 63
Abelson tyrosine-protein kinase 2 Inhibitor 3'',5''-dimethoxy-... 3 9
Steryl-sulfatase Inhibitor 2-ethylestradiol 3,17-o,o-bis-sulfa... 1 2
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 4-(1,... 3 31
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 4 37
Indoleamine 2,3-dioxygenase 1 Inhibitor Naphthalene-1,4-diol F... 2 4
Tyrosinase Inhibitor 4-(6-hydroxynaphthalen-2-yl)benzene-1,3-d... 4 2
Tyrosinase Inhibitor Kazinol S Family 1 0
Tyrosinase Inhibitor 4-adamantyl Resorcinol Family 1 1
DNA polymerase Inhibitor 3alpha-o-trans-p-coumaroyl-7-labden-1... 1 13
Sodium/glucose cotransporter 2 and Sodium/glucose cotransporte... 3 19
Estrogen receptor beta and Estrogen receptor ligand 3-fluoro-4... 6 42
Estrogen receptor and Estrogen receptor beta ligand 10-[(8S,9S... 1 0
Estrogen receptor beta and Estrogen receptor ligand 3-chloro-4... 2 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 14
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 4 0
Steryl-sulfatase inhibitor (8R,9S,13S,14S,17R)-17-[(3-bromophe... 1 1
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 5-(2-... 3 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 1-[3,... 4 0
Retinoic acid receptor beta ligand Adarotene family 1 0
Acenes Metabolite 2-Methyl-1,4-naphthalenediol bis(dihydrogen ... 2 2
Phenols and Derivatives Metabolite 2-(Ethoxymethyl)phenol Family 1 14
[(E)-3-carboxy-2-(5-methyl-2-oxidophenyl)prop-2-enyl]-(2-pheny... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00252204 CHEMBL131627 Bioactive (2s,4s,4as,6r,8ar)-6-(hydroxymethyl)-4-[2-hydroxy-4-(2-methyloctan-2-yl)phenyl]decahydronaphthalen-2-ol
CFAMM00252211 CHEMBL65192 Bioactive SureCN563831
CFAMM00252217 CHEMBL163701 Bioactive CP-47497
CFAMM00252215 DNC006016 Investigative Drug CP-55940
CFAMM00252208 DNC009187 Investigative Drug halisulfate 1
CFAMM00252207 DNC009186 Investigative Drug hydrohalisulfate 1

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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