CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1859
Family Name M-phase inducer phosphatase 3 Inhibitor NSC-663284 Family
No. of Seeds 1 No. of Other Members 12
Family Centroid CFAMM00252404 Functional Category Investigative Drug with Natural Product
Superfamily Cytochrome P450 11B1, mitochondrial Inhibitor Metyrapone Superfamily
Class Class 255

Cousin Family NamesSeedsMembers
SUR2-type K(ATP) channel Ligand Nicorandil Family 5 85
Mitogen-activated protein kinase 14 Inhibitor Losmapimod Family 5 154
Gamma-aminobutyric acid receptor Ligand E-2007 Family 7 118
Substance-P receptor Ligand TAK-637 Family 18 63
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 24 50
D(4) dopamine receptor Ligand ABT-670 Family 4 14
C-C chemokine receptor type 5 Ligand GT-1282 Family 21 14
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 4 6
Bifunctional epoxide hydrolase 2 Inhibitor N-(3,3-diphenyl-pro... 6 14
Glutamate receptor 1 Ligand Piriqualone Family 8 67
Amine oxidase [flavin-containing] A Inhibitor 6-chloro-n-(2-mo... 5 3
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 1 4
Dipeptidyl peptidase 4 inhibitor (1S,3S,5S)-2-[(2S)-2-amino-2-... 3 5
Metabotropic glutamate receptor 5 ligand AGN-PC-0A9SVV family 2 12
Histamine H3 receptor ligand SureCN1857507 family 1 4
Neutrophil elastase inhibitor N-[(2S)-3-methyl-1-oxo-1-[(2S)-2... 4 4
Metabotropic glutamate receptor 5 ligand AGN-PC-09SALK family 2 15
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor 4-(5,7... 2 9
Metabotropic glutamate receptor 5 ligand 3-methyl-1-[2-[3-(tri... 3 1
NP 2-(2-hydroxyethyl)-8-isopentylpyrido[4,3-b][1,6]naphthyridi... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00252404 DNC006028 Investigative Drug NSC-663284

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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