CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1861
Family Name A disintegrin and metalloproteinase with thrombospondin motifs 4 Inhibitor (r)-2-(biphenyl-4-sulfonylamino)-propionic Acid Family
No. of Seeds 6 No. of Other Members 33
Family Centroid CFAMM00252428 Functional Category Investigative Drug
Superfamily A disintegrin and Stromelysin-1 Binder Superfamily
Class Class 2272

Cousin Family NamesSeedsMembers
Cathepsin K Inhibitor Odanacatib Family 33 84
Capsid scaffolding protein Inhibitor O-benzylsulfonyl-serine F... 1 2
72 kDa type IV collagenase and Stromelysin-1 Inhibitor PD-1694... 10 10
Disintegrin and metalloproteinase domain-containing protein 17... 7 39
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 2 1
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 6
Pol polyprotein inhibitor Lysine Sulfonamide 11c family 3 73
Collagenase 3 and Neutrophil collagenase inhibitor 2-[2-(4-phe... 1 0
Stromelysin-1 and 72 kDa type IV collagenase inhibitor SureCN7... 1 1
Thromboxane A2 receptor ligand (Z)-7-[(1R,2S)-2-(benzenesulfon... 1 13
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R)-2-... 2 0
Prostaglandin D2 receptor and Thromboxane A2 receptor ligand (... 3 15
Stromelysin-1 and 72 kDa type IV collagenase inhibitor (2S)-2-... 1 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 1 2
72 kDa type IV collagenase and Collagenase 3 inhibitor 5-pheny... 1 1
Stromelysin-1 and 72 kDa type IV collagenase inhibitor SureCN4... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00252433 CHEMBL47254 Bioactive SureCN7866198
CFAMM00252426 CHEMBL43113 Bioactive SureCN7870619
CFAMM00252424 CHEMBL330028 Bioactive AGN-PC-04TKJN
CFAMM00252462 CHEMBL418442 Bioactive SureCN7406959
CFAMM00252428 DNC006031 Investigative Drug (R)-2-(biphenyl-4-sulfonylamino)-propionic acid
CFAMM00252452 DNC009408 Investigative Drug 2-(biphenyl-4-ylsulfonamido)pentanedioic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27526 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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