CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1864
Family Name Epidermal growth factor receptor Ligand 4-acrylamido-n-(3-bromophenyl)-2-hydroxybenzamide Family
No. of Seeds 2 No. of Other Members 20
Family Centroid CFAMM00252569 Functional Category Investigative Drug with Natural Product
Superfamily Estrogen receptor beta and Epidermal growth factor receptor Binder Superfamily
Class Class 798

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 1 Inhibitor Mesalazine Family 2 30
Serum albumin Inhibitor Iodipamide Family 2 23
Cystic fibrosis transmembrane conductance regulator Inhibitor ... 2 9
Epidermal growth factor receptor and Tyrosine-protein kinase L... 1 26
Tyrosine-protein kinase SYK Inhibitor N-benzyl-4-(2,5-dihydrox... 1 4
High affinity nerve growth factor receptor and RAF proto-oncog... 3 29
Macrophage migration inhibitory factor Inhibitor 2-(4-hydroxys... 8 19
Estradiol 17-beta-dehydrogenase 1 Inhibitor 2-hydroxy-n,6-bis(... 2 7
G-protein coupled receptor 35 and Cellular tumor antigen p53 l... 1 1
Bifunctional epoxide hydrolase 2 inhibitor Urea-based compound... 1 3
Amine oxidase [flavin-containing] B and Adenosine receptor A2b... 2 2
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 1 0
Neprilysin inhibitor 5-[[(2S,4S)-2-benzyl-4-carboxy-5-phenylpe... 1 0
DNA-dependent protein kinase catalytic subunit and DNA-(apurin... 2 4
Glycogen synthase kinase-3 beta and Glycogen synthase kinase-3... 5 0
Serine/threonine-protein kinase pim-3 and Homeodomain-interact... 1 5
Nuclear receptor ROR-gamma and Lethal factor ligand NSC211094 ... 1 3
Putative NP ZINC08880095 Family 2 0


External ID

Functional Category

Molecule Name

CFAMM00252569 DNC006035 Investigative Drug 4-acrylamido-N-(3-bromophenyl)-2-hydroxybenzamide
CFAMM00252568 DNC006036 Investigative Drug 5-acrylamido-N-(3-bromophenyl)-2-hydroxybenzamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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