CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1873
Family Name Macrophage migration inhibitory factor Inhibitor 3,3,3-tris(4-chlorophenyl)propanoic Acid Family
No. of Seeds 4 No. of Other Members 16
Family Centroid CFAMM00252928 Functional Category Investigative Drug
Superfamily Amyloid precursor protein secretase Inhibitor CHF-5074 Superfamily
Class Class 1213

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Flurbiprofen Family 18 294
Amyloid precursor protein secretase Inhibitor CHF-5074 Family 1 1
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 2-[9-... 2 15
Free fatty acid receptor 1 and Free fatty acid receptor 4 liga... 1 1
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 4


External ID

Functional Category

Molecule Name

CFAMM00252930 CHEMBL1911409 Bioactive 2-[2-(3-chlorophenyl)-2-adamantyl]acetic acid
CFAMM00252929 CHEMBL1911408 Bioactive 2-[2-(4-chlorophenyl)-2-adamantyl]acetic Acid
CFAMM00252922 CHEMBL1911413 Bioactive 2-[2-[(2-chlorophenyl)methyl]-2-adamantyl]acetic acid
CFAMM00252928 DNC006067 Investigative Drug 3,3,3-tris(4-chlorophenyl)propanoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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