CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1876
Family Name Gonadotropin-releasing hormone receptor Ligand TAK-013 Family
No. of Seeds 19 No. of Other Members 10
Family Centroid CFAMM00252962 Functional Category Investigative Drug
Superfamily Gonadotropin-releasing hormone receptor Ligand TAK-013 Superfamily
Class Class 2149

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase Chk1 Inhibitor AZD7762 Family 26 90
Gonadotropin-releasing hormone receptor Ligand T-98475 Family 16 21
Monocarboxylate transporter 1 inhibitor 3-methyl-1-(2-methylpr... 9 7
Thyroid hormone receptor beta ligand CHEMBL1554195 family 1 2
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 0
Survival motor neuron protein and Nuclear receptor ROR-gamma l... 1 2
Flap endonuclease 1 and DNA repair protein complementing XP-G ... 2 0
Melanin-concentrating hormone receptor 1 ligand (3S)-3-[[5-[4-... 1 1
Monocarboxylate transporter 1 and Cytochrome P450 2C9 inhibito... 9 0
Monocarboxylate transporter 1 and Cytochrome P450 2C9 inhibito... 1 0
Gonadotropin-releasing hormone receptor ligand AGN-PC-00CZII f... 5 0
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 3
Serine/threonine-protein kinase Chk1 inhibitor SureCN1564756 f... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00253002 CHEMBL1800669 Bioactive 1-[4-[1-[(2,6-difluorophenyl)methyl]-3-(2-methoxyethyl)-5-[[2-methoxyethyl(methyl)amino]methyl]-2,4-dioxothieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea
CFAMM00252999 CHEMBL21217 Bioactive 1-[4-[5-[[benzyl(methyl)amino]methyl]-1-[(2,6-difluorophenyl)methyl]-2,4-dioxo-3-phenylthieno[2,3-d]pyrimidin-6-yl]phenyl]-3-ethoxyurea
CFAMM00252988 CHEMBL277214 Bioactive 1-[4-[5-[[benzyl(methyl)amino]methyl]-1-[(2,6-difluorophenyl)methyl]-2,4-dioxo-3-phenylthieno[2,3-d]pyrimidin-6-yl]phenyl]-3-hydroxyurea
CFAMM00252997 CHEMBL280126 Bioactive 1-[4-[5-[[benzyl(methyl)amino]methyl]-1-[(2,6-difluorophenyl)methyl]-2,4-dioxo-3-phenylthieno[2,3-d]pyrimidin-6-yl]phenyl]-3-propan-2-ylurea
CFAMM00252984 CHEMBL1800670 Bioactive 1-[4-[1-[(2,6-difluorophenyl)methyl]-3-(2-ethoxyethyl)-5-[[2-methoxyethyl(methyl)amino]methyl]-2,4-dioxothieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea
CFAMM00253008 CHEMBL1800666 Bioactive 1-[4-[1-[(2,6-difluorophenyl)methyl]-5-[[methyl-[2-(2-oxopyrrolidin-1-yl)ethyl]amino]methyl]-2,4-dioxo-3-phenylthieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea
CFAMM00252970 CHEMBL280213 Bioactive N-[4-[5-[[benzyl(methyl)amino]methyl]-1-[(2,6-difluorophenyl)methyl]-2,4-dioxo-3-phenylthieno[2,3-d]pyrimidin-6-yl]phenyl]-2-methylpropanamide
CFAMM00252995 CHEMBL332355 Bioactive N-[4-[5-[[benzyl(methyl)amino]methyl]-1-[(2,6-difluorophenyl)methyl]-2,4-dioxo-3-phenylthieno[2,3-d]pyrimidin-6-yl]phenyl]acetamide
CFAMM00252983 CHEMBL1800150 Bioactive 1-[4-[1-[(2,6-difluorophenyl)methyl]-3-(2-hydroxyethyl)-5-[[2-methoxyethyl(methyl)amino]methyl]-2,4-dioxothieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea
CFAMM00253007 CHEMBL1800667 Bioactive 1-[4-[1-[(2,6-difluorophenyl)methyl]-5-[[methyl-[2-[methyl(methylsulfonyl)amino]ethyl]amino]methyl]-2,4-dioxo-3-phenylthieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea
CFAMM00252969 CHEMBL280212 Bioactive N-[4-[5-[[benzyl(methyl)amino]methyl]-1-[(2,6-difluorophenyl)methyl]-2,4-dioxo-3-phenylthieno[2,3-d]pyrimidin-6-yl]phenyl]benzamide
CFAMM00252982 CHEMBL1800151 Bioactive 1-[4-[1-[(2,6-difluorophenyl)methyl]-3-(2-hydroxy-2-methylpropyl)-5-[[2-methoxyethyl(methyl)amino]methyl]-2,4-dioxothieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea
CFAMM00252992 CHEMBL21936 Bioactive 1-[4-[5-[[benzyl(methyl)amino]methyl]-1-[(2,6-difluorophenyl)methyl]-2,4-dioxo-3-phenylthieno[2,3-d]pyrimidin-6-yl]phenyl]-3-propan-2-yloxyurea
CFAMM00253003 CHEMBL1800668 Bioactive 1-[4-[1-[(2,6-difluorophenyl)methyl]-5-[[2-methoxyethyl(methyl)amino]methyl]-2,4-dioxo-3-phenylthieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methoxyurea
CFAMM00252991 CHEMBL2092994 Bioactive 1-[4-[5-[[benzyl(methyl)amino]methyl]-1-[(2,6-difluorophenyl)methyl]-2,4-dioxo-3-phenylthieno[2,3-d]pyrimidin-6-yl]phenyl]-3-methylurea
CFAMM00252962 DNC006081 Investigative Drug TAK-013

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27620 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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