CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1879
Family Name 3-oxo-5-alpha-steroid 4-dehydrogenase 2 Inhibitor 4-[4-(benzylamino)benzoyl]benzoic Acid Family
No. of Seeds 2 No. of Other Members 19
Family Centroid CFAMM00253174 Functional Category Investigative Drug
Superfamily 3-oxo-5-alpha-steroid 4-dehydrogenase 2 Inhibitor 4-[4-(benzylamino)benzoyl]benzoic Acid Superfamily
Class Class 2279

Cousin Family NamesSeedsMembers
Sodium channel protein type 10 subunit alpha Ligand Tetracaine... 6 166
Retinoic acid receptor alpha Ligand Tamibarotene Family 5 95
Prostaglandin G/H synthase 1 Inhibitor Mesalazine Family 2 30
Prostaglandin G/H synthase 2 Inhibitor Mefenamic Acid Family 7 137
Cyclooxygenase Inhibitor Meclofenamic Acid Family 4 11
Serum albumin Inhibitor Iodipamide Family 2 23
Beta-3 adrenergic receptor Ligand GW-427353 Family 3 5
Histone deacetylase 1 and Tyrosine-protein kinase JAK2 Inhibit... 2 3
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
New permeability pathways Inhibitor 5-nitro-2-(3-phenylpropyla... 1 13
Beta-lactamase Inhibitor 4-[(methylsulfonyl)amino]benzoic Acid... 1 7
Neuraminidase Inhibitor 4-(acetylamino)-3-amino Benzoic Acid F... 2 27
Tyrosine-protein phosphatase non-receptor type 1 Ligand 2-(oxa... 3 11
Dihydroorotate dehydrogenase Inhibitor 2-(2-bromo-2-naphthamid... 1 2
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 17 50
Bifunctional epoxide hydrolase 2 Inhibitor 4-(3-adamantan-1-yl... 3 12
Carbonic anhydrase 2 Inhibitor 4-(4-tert-butylbenzylideneamino... 3 15
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 3 8
Integrin beta-3 and Integrin alpha-IIb inhibitor 2-[7-[[4-(N'-... 7 15
Prostaglandin E2 receptor EP4 subtype ligand SureCN3567929 family 10 3
Free fatty acid receptor 1 ligand AGN-PC-03ZC6J family 2 14
Diacylglycerol O-acyltransferase 1 inhibitor Urea-based Analog... 7 5
Integrin beta-1 and Integrin alpha-4 inhibitor 4-[[1-[2-[4-[(2... 2 8
Bifunctional epoxide hydrolase 2 inhibitor 6-[[1-(2,4-dimethyl... 1 3
Mitogen-activated protein kinase 14 inhibitor ethyl 3-(2,4-dif... 5 1
Collagenase 3 inhibitor 4-[[4-oxo-6-(3-phenylprop-1-ynyl)quina... 2 9
Integrin beta-3 and Integrin alpha-V inhibitor SureCN7494201 f... 5 14
Retinoic acid receptor beta and Retinoic acid receptor gamma l... 4 7
Coagulation factor X and Tissue factor inhibitor AGN-PC-02WN8Y... 7 22
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 7 6
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 4-[[1... 2 5
Tankyrase-2 inhibitor 3-chloro-4-(4-methyl-2-oxo-1H-quinolin-7... 1 2
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme ... 1 3
Protein farnesyltransferase subunit beta and Protein farnesylt... 2 4
DNA polymerase beta and Nuclear receptor ROR-gamma ligand AN-3... 1 3
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 1 1
Glucocorticoid receptor ligand AGN-PC-01X8JJ family 1 0
Integrin beta-3 and Integrin alpha-IIb inhibitor AGN-PC-075JCL... 1 0
NP Methyl 3-acetyl-4-oxo-1,4-dihydroquinoline-8-carboxylate Fa... 2 0
Putative NP ZINC35345693 Family 7 1
Putative NP ZINC12659473 Family 5 0
7-(4-chlorophenyl)-3b,6,6a,7,9,9a,10,12a-octahydrocyclopenta[4... 8 0
3-[(Z)-3-chlorobut-2-enyl]-2-methyl-4-oxo-1H-quinoline-6-carbo... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00253174 DNC006086 Investigative Drug 4-[4-(benzylamino)benzoyl]benzoic acid
CFAMM00253188 DNC010018 Investigative Drug 4-(4-hydroxybenzylideneamino)benzoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27029 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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