CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1881
Family Name 72 kDa type IV collagenase and Macrophage metalloelastase Inhibitor 4-(4-(dec-1-ynyl)phenyl)-4-oxobutanoic Acid Family
No. of Seeds 2 No. of Other Members 5
Family Centroid CFAMM00253200 Functional Category Investigative Drug
Superfamily Prostaglandin G/H synthase 2 Inhibitor Ketoprofen Superfamily
Class Class 368

Cousin Family NamesSeedsMembers
Antithrombin-III Inhibitor Heparin Family 2 74
Retinoid X receptor Ligand Bexarotene Family 7 492
Aldehyde oxidase inhibitor para-naphthoquinone Menadione Family 22 503
Cyclooxygenase Inhibitor Flurbiprofen Family 18 294
Prostaglandin G/H synthase 2 Inhibitor Ketoprofen Family 5 84
Vitamin K epoxide reductase complex subunit 1 Inhibitor Phenin... 5 44
Noradrenergic re-uptake and Serotonin re-uptake Inhibitor Diet... 29 276
DNA topoisomerase 2-beta Inhibitor Salvicine Family 2 9
CPI-613 family 4 35
Dihydroorotate dehydrogenase Inhibitor Polyporic Acid Family 4 13
Carbonic anhydrase 2 Inhibitor 4-(hydroxymercury)benzoic Acid ... 7 97
Beta-lactamase Inhibitor 4-carboxyphenylboronic Acid Family 1 1
Cathepsin L1 Inhibitor Biphenyl-4-yl-acetaldehyde Family 2 86
Carboxypeptidase B2 Inhibitor Dl-benzylsuccinic Acid Family 1 11
Cytosolic phospholipase A2 Inhibitor 1,1,1,2,2-pentafluoro-8-p... 11 18
Liver carboxylesterase 1 Inhibitor 1,2-bis(2,3,6-trifluorophen... 16 11
Liver carboxylesterase 1 Inhibitor 1-(4-chloro-phenyl)-2-pheny... 5 47
Glutamate carboxypeptidase 2 Inhibitor 2-(3-carboxybenzyl)succ... 2 7
Glutamate carboxypeptidase 2 Inhibitor 2-(3-cyanobenzyl)-5-mer... 1 0
Glutamate carboxypeptidase 2 Inhibitor 3-(2-carboxy-6-mercapto... 9 4
Thyroid hormone receptor alpha and Thyroid hormone receptor be... 2 8
Thyroid hormone receptor beta Ligand (4-hexylphenyl)(oxiran-2-... 1 16
Liver carboxylesterase 1 Inhibitor Acenanthrene-9,10-dione Family 2 12
Collagenase 3 and Macrophage metalloelastase Inhibitor 5-(4'-c... 4 43
4-hydroxyphenylpyruvate dioxygenase Inhibitor 2-(2-iodo-benzoy... 3 1
Neuraminidase Inhibitor (e,e)-1,7-diphenyl-4,6-heptadien-3-one... 2 5
Retinoic acid receptor RXR-alpha and Retinoic acid receptor RX... 9 10
Arachidonate 15-lipoxygenase inhibitor SureCN9469035 family 6 40
Free fatty acid receptor 1 ligand AGN-PC-0CCG7G family 1 2
Retinal dehydrogenase 1 and Microtubule-associated protein tau... 1 7
Integrase inhibitor AGN-PC-00QHSA family 1 2
Putative NP ZINC14410655 Family 6 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00253198 DNC007840 Investigative Drug 4-(4-hexylphenyl)-4-oxobut-2-enoic acid
CFAMM00253200 DNC006096 Investigative Drug 4-(4-(dec-1-ynyl)phenyl)-4-oxobutanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

60878 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543