CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1884
Family Name 72 kDa type IV collagenase and Stromelysin-1 Inhibitor PD-169469 Family
No. of Seeds 10 No. of Other Members 10
Family Centroid CFAMM00253403 Functional Category Investigative Drug
Superfamily A disintegrin and Stromelysin-1 Binder Superfamily
Class Class 2272

Cousin Family NamesSeedsMembers
A disintegrin and metalloproteinase with thrombospondin motifs... 6 33
Disintegrin and metalloproteinase domain-containing protein 17... 7 39
Voltage-dependent calcium channel gamma-1 subunit Ligand 4-(4-... 3 0
72 kDa type IV collagenase and Collagenase 3 inhibitor AGN-PC-... 2 1
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 6
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 6 1
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-N-... 10 1
Collagenase 3 and Neutrophil collagenase inhibitor 2-[2-(4-phe... 1 0
Stromelysin-1 and 72 kDa type IV collagenase inhibitor SureCN7... 1 1
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2S)-2-... 2 5
72 kDa type IV collagenase and Collagenase 3 inhibitor (2R)-2-... 2 0
Stromelysin-1 and 72 kDa type IV collagenase inhibitor (2S)-2-... 1 0
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00253401 CHEMBL421882 Bioactive SureCN4424095
CFAMM00253394 CHEMBL295871 Bioactive 4-benzylsulfanyl-2-[[4-(4-bromophenyl)phenyl]sulfonylamino]butanoic acid
CFAMM00253400 CHEMBL433262 Bioactive (2R)-2-[[4-(4-bromophenyl)phenyl]sulfonylamino]-N-hydroxy-3-methylbutanamide
CFAMM00253406 CHEMBL47076 Bioactive 4-benzylsulfonyl-2-[[4-(4-bromophenyl)phenyl]sulfonylamino]butanoic acid
CFAMM00253399 CHEMBL44898 Bioactive SureCN7870635
CFAMM00253391 CHEMBL44062 Bioactive SureCN7409456
CFAMM00253403 DNC006101 Investigative Drug PD-169469

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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