CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1888
Family Name Metabotropic glutamate receptor 5 Ligand N-[4-(3-pyridylethynyl)-2-thiazolyl]acetamide Family
No. of Seeds 2 No. of Other Members 10
Family Centroid CFAMM00253500 Functional Category Investigative Drug
Superfamily Cyclin-dependent kinase 5 and Poly [ADP-ribose] polymerase 1 Binder Superfamily
Class Class 1600

Cousin Family NamesSeedsMembers
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing... 3 16
DNA primase Inhibitor Bay 57-1293 Family 1 2
Cyclin-dependent kinase 2 Inhibitor 4-(2,4-dimethyl-thiazol-5-... 2 14
Metabotropic glutamate receptor 5 Ligand 2-methyl-4-(pyridin-3... 10 35
TGF-beta receptor type-1 Ligand 4-pyridin-2-yl-5-quinolin-4-yl... 4 23
Mitogen-activated protein kinase 14 Inhibitor 4-(2-ethyl-4-m-t... 14 41
C-C chemokine receptor type 4 Ligand N-(naphthalen-1-yl)-4-neo... 5 78
C-C chemokine receptor type 4 Ligand N-(4-tert-butylthiazol-2-... 3 9
Cyclin-dependent kinase 5 Inhibitor 1-phenyl-3-(2-(pyridin-4-y... 3 53
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-264... 6 32
Amine oxidase [flavin-containing] B Inhibitor 2-(2-cyclohexyli... 6 44
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 2-[3-(4-acet... 4 12
Neuropeptide Y receptor type 5 ligand N-[[(1S,5R)-3-(1-phenyle... 5 1
Neuropeptide Y receptor type 5 ligand 2-phenyl-1-[(1R,5S)-6-[[... 9 11
Neuropeptide Y receptor type 5 and Potassium voltage-gated cha... 2 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 8
Amine oxidase [flavin-containing] B inhibitor 4-(4-fluoropheny... 3 4
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 13 2
Platelet-activating factor receptor ligand Foropafant family 2 0
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 7 21
Mitogen-activated protein kinase 14 inhibitor N-[4-[2-ETHYL-4-... 4 5
Aromatase inhibitor 2-(2-chloropyridin-4-yl)-4-pyridin-3-yl-1,... 1 1
Vascular endothelial growth factor receptor 2 ligand AC1NS6KN ... 4 5
Vascular endothelial growth factor receptor 2 ligand N-(1,3-Th... 4 4
Mitogen-activated protein kinase 14 inhibitor 303163-37-3 family 1 2
Tyrosine-protein kinase Lck inhibitor AGN-PC-03HL8Q family 4 0
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... 4 1
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 2 4
Cyclin-dependent kinase 5 and G1/S-specific cyclin-E1 inhibito... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00253500 DNC006117 Investigative Drug N-[4-(3-pyridylethynyl)-2-thiazolyl]acetamide
CFAMM00253499 DNC006118 Investigative Drug 4-(3-pyridylethynyl)-2-thiazolylamine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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