CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1912
Family Name Oestrogen receptor and Estrogen receptor beta Ligand Estrogen Platinum(ii) Hybrid Derivative Family
No. of Seeds 7 No. of Other Members 2
Family Centroid CFAMM00254115 Functional Category Investigative Drug
Superfamily Oestrogen receptor and Estrogen receptor beta Binder Superfamily
Class Class 1979

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
Citric Acid family 2 58
Nicotinic acetylcholine receptor Ligand AZD0328 Family 11 97
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Lig... 9 115
Hemoglobin subunit alpha Inhibitor 2-[(2-methoxy-5-methylpheno... 5 48
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 5 23
Estradiol 17-beta-dehydrogenase 1 Inhibitor 4'-(6-methoxypyrid... 5 34
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 12 3
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 13 26
Steroid 17-alpha-hydroxylase/17,20 lyase and Cytochrome P450 1... 7 6
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 2 5
Estradiol 17-beta-dehydrogenase 1 Inhibitor N(pyridin-4-ylmeth... 2 4
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 4 35
Cytochrome P450 11B1, mitochondrial Inhibitor 5-(6-methoxynaph... 7 4
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor 5-hexy... 4 5
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3,3'-pyrazine-2,5-... 2 14
Potassium voltage-gated channel subfamily A member 5 Ligand 2-... 5 69
DNA topoisomerase 1 Inhibitor 3-(4-phenyl-2,4'-bipyridin-6-yl)... 4 13
Cytochrome P450 11B1, mitochondrial Inhibitor Metyrapol Family 3 41
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 38 35
Histamine H1 receptor and Potassium voltage-gated channel subf... 3 1
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 3 18
Serine/threonine-protein kinase B-raf inhibitor AGN-PC-00CFYH ... 2 1
D(1A) dopamine receptor and D(2) dopamine receptor ligand (6aR... 3 6
Glucocorticoid receptor ligand SureCN3894124 family 3 0
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 7 1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 2 4
Nuclear receptor ROR-gamma and Induced myeloid leukemia cell d... 1 1
Estrogen receptor and Estrogen receptor beta ligand AGN-PC-074... 1 0
(E)-3-(2-hydroxyphenyl)-1-pyridin-4-ylprop-2-en-1-one NP (e)-3... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00254128 CHEMBL310662 Bioactive (13S)-13-methyl-17-pyridin-3-yl-6,7,8,9,11,12,14,15-octahydrocyclopenta[a]phenanthren-3-ol
CFAMM00254122 DNC006184 Investigative Drug 16-(pyridin-3-yl)methylene-estradiol
CFAMM00254121 DNC006182 Investigative Drug 16-(pyridin-4-yl)methylene-estradiol
CFAMM00254120 DNC006183 Investigative Drug 16-(pyridin-2-yl)methylene-estradiol
CFAMM00254119 DNC006175 Investigative Drug 16-(pyridin-4-yl)methyl-estradiol
CFAMM00254118 DNC006177 Investigative Drug 16-(pyridin-3-yl)methyl-estradiol
CFAMM00254117 DNC006176 Investigative Drug 16-(pyridin-2-yl)methyl-estradiol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26413 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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