CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1923
Family Name Sodium-dependent dopamine transporter and Sodium-dependent noradrenaline transporter Inhibitor 1-(4-nitrophenyl)-2-pyrrolidin-1-yl-pentan-1-one Family
No. of Seeds 2 No. of Other Members 13
Family Centroid CFAMM00254287 Functional Category Investigative Drug
Superfamily Sodium-dependent dopamine transporter and Sodium-dependent noradrenaline transporter Binder Superfamily
Class Class 2295

Cousin Family NamesSeedsMembers
D(2) dopamine receptor and D(3) dopamine receptor ligand indol... 4 123
Sodium channel protein type 5 subunit alpha Ligand Procainamid... 7 291
4-hydroxyphenylpyruvate dioxygenase Inhibitor Nitisinone Family 4 43
Cholesterol side-chain cleavage enzyme, mitochondrial and Arom... 9 26
Motilin receptor Ligand GSK962040 Family 30 457
Poly [ADP-ribose] polymerase 1 Inhibitor BSI-201 Family 3 16
Histone deacetylase 1 Inhibitor AN-9 Family 31 282
K-604 family 4 71
Pan-DAC Inhibitor AR-42 Family 21 153
Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
Fumarate reductase flavoprotein subunit Inhibitor 2-heptyl-4-h... 3 16
Liver carboxylesterase 1 Inhibitor 1-methyl-1h-indole-2,3-dion... 10 35
Potassium voltage-gated channel subfamily A member 5 Ligand N-... 8 32
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Aromatase Inhibitor 3-(4-amino-phenyl)-1-methyl-pyrrolidine-2,... 4 8
Liver carboxylesterase 1 Inhibitor 1-(4-nitro-phenyl)-2-phenyl... 2 7
Acetylcholinesterase Inhibitor Bw-28c51 Family 3 8
Cannabinoid receptor 2 Ligand N1-(4-bromophenyl)-n2,n2-dipenty... 4 21
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 12
Mitogen-activated protein kinase 14 Inhibitor Dihydro-quinolin... 3 14
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 7
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 15 129
5-hydroxytryptamine receptor 2A Ligand N-(1-(4-nitrobenzyl)pip... 4 6
D(4) dopamine receptor ligand AGN-PC-074VC9 family 2 3
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-04UEDE family 7 17
Acetylcholinesterase inhibitor CHEMBL1651130 family 2 3
Peptide deformylase inhibitor (2R)-2-[[formyl(hydroxy)amino]me... 2 1
Amyloid beta A4 protein inhibitor AGN-PC-08WTQK family 1 3
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 4 0
Histamine H3 receptor ligand SureCN3058680 family 4 0
Transient receptor potential cation channel subfamily A member... 1 1
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 1 0
Neutrophil elastase inhibitor 1-[(2S)-3-methyl-2-[(4-nitrobenz... 1 1
Kappa-type opioid receptor and Delta-type opioid receptor liga... 3 1
Carbonic anhydrase 9 and Carbonic anhydrase 12 inhibitor AGN-P... 2 0
Glucose-dependent insulinotropic receptor ligand AGN-PC-04UO8L... 2 2
Histone deacetylase 6 and Histone deacetylase 1 inhibitor AGN-... 1 2
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 1 1
Polymerase acidic protein inhibitor (Z)-4-hydroxy-2-oxo-4-(4-p... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00254287 DNC006222 Investigative Drug 1-(4-nitrophenyl)-2-pyrrolidin-1-yl-pentan-1-one
CFAMM00254286 DNC009769 Investigative Drug 1-(4-aminophenyl)-2-pyrrolidin-1-yl-pentan-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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