CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1945
Family Name Dipeptidyl peptidase 4 Inhibitor (2-chloro-6-phenoxyphenyl)methanamine Family
No. of Seeds 17 No. of Other Members 24
Family Centroid CFAMM00254755 Functional Category Investigative Drug
Superfamily Dipeptidyl peptidase 4 Inhibitor (2-chloro-6-phenoxyphenyl)methanamine Superfamily
Class Class 1928

Cousin Family NamesSeedsMembers
Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Alpha adrenergic receptor Ligand Phenoxybenzamine Family 4 63
Sodium channel protein type 5 subunit alpha Ligand Mexiletine ... 7 74
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Serine/threonine-protein kinase PLK1 Inhibitor On 019190.na Fa... 16 138
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 4 35
Substance-P receptor Ligand Ezlopitant Family 10 207
Dapoxetine family 3 40
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 33 83
Extracellular calcium-sensing receptor Ligand Nps 568 Family 5 54
Histamine H3 receptor Ligand A-331440 Family 6 7
Histamine H3 receptor Ligand UCL-2138 Family 23 172
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 5 11
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 7 22
Adenosine receptor A3 and Muscarinic acetylcholine receptor M2... 4 31
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 41
C-C chemokine receptor type 5 Ligand N-(2-(4-chlorobenzyloxy)-... 3 13
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 11
Sodium-dependent serotonin transporter Inhibitor 4-(2-((dimeth... 3 1
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 13
Fatty-acid amide hydrolase 1 Inhibitor 3-(trifluoromethyl)phen... 3 0
5-hydroxytryptamine receptor 2A Ligand C-(9h-xanthen-9-yl)-met... 3 5
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 2 3
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Inhibitor 2... 1 9
D(4) dopamine receptor ligand AGN-PC-0073PO family 7 10
Sigma non-opioid intracellular receptor 1 and 3-beta-hydroxyst... 15 11
Substance-P receptor ligand (2S,3S)-2-(3-chlorophenyl)-N-[(2,4... 1 0
D(4) dopamine receptor and D(3) dopamine receptor ligand N-[2-... 6 15
Sodium-dependent serotonin transporter and Sodium-dependent no... 1 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 6 21
Nitric oxide synthase, inducible and Cytochrome P450 2D6 inhib... 2 1
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 5
Histamine H3 receptor ligand AGN-PC-0765YW family 1 4
Sodium-dependent noradrenaline transporter and Sodium-dependen... 14 1
Sodium-dependent serotonin transporter and Histamine H3 recept... 4 1
Sodium-dependent serotonin transporter and Histamine H3 recept... 7 0
Histamine H3 receptor and Sodium-dependent serotonin transport... 4 0
Histamine H3 receptor and Sodium-dependent serotonin transport... 6 1
Sodium-dependent serotonin transporter inhibitor 4-(4-chloro-2... 2 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 0
Scytalone dehydratase inhibitor 2-cyano-N-[(1S,2R)-1-(2-cyanop... 5 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 2 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 1 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 1
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 1 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 0
Sodium-dependent serotonin transporter and Potassium voltage-g... 1 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 0
Sodium-dependent serotonin transporter inhibitor AGN-PC-078ZCU... 1 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 1 1
Sodium-dependent serotonin transporter inhibitor 1-[5-methoxy-... 1 0
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 2 2
D(4) dopamine receptor ligand 4-[(4-chlorophenyl)methyl]-2-[(2... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00254772 CHEMBL451330 Bioactive AGN-PC-078WIT
CFAMM00254757 CHEMBL452091 Bioactive AGN-PC-078W2Z
CFAMM00254763 CHEMBL443922 Bioactive AGN-PC-077U9M
CFAMM00254755 DNC006310 Investigative Drug (2-chloro-6-phenoxyphenyl)methanamine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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