CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1946
Family Name Dipeptidyl peptidase 4 Inhibitor 2-(2-chlorophenyl)-2-morpholinoethanamine Family
No. of Seeds 2 No. of Other Members 34
Family Centroid CFAMM00254783 Functional Category Investigative Drug
Superfamily Dipeptidyl peptidase 4 Inhibitor 2-(2-chlorophenyl)-2-morpholinoethanamine Superfamily
Class Class 2301

Cousin Family NamesSeedsMembers
Voltage-dependent T-type calcium channel subunit alpha-1H liga... 10 397
Noradrenergic re-uptake and Serotonin re-uptake Inhibitor Sibu... 7 127
Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140
Amine oxidase [flavin-containing] A Inhibitor Moclobemide Family 5 255
Nuclear receptor subfamily 1 group I member 3 ligand piperazin... 3 82
Acetylcholinesterase Inhibitor Ambenonium Family 4 71
Muscarinic acetylcholine receptor M3 Ligand Diphemanil Methyls... 22 45
Dopamine reuptake and Noradrenergic re-uptake Inhibitor Dov 21... 16 89
5-hydroxytryptamine receptor 2C Ligand Lorcaserin Family 8 38
Substance-P receptor Ligand Vestipitant Family 14 137
Zicronapine family 43 62
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 11 67
Reverse transcriptase Inhibitor 3-benzylamino-5-ethyl-6-methyl... 2 24
Prothrombin Inhibitor D-leucyl-n-(3-chlorobenzyl)-l-prolinamid... 18 168
Beta-secretase 1 Inhibitor N-(1-benzylpiperidin-4-yl)-4-sulfan... 7 62
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 5-(4-chloro-... 3 7
Adenosine receptor A3 and Glutamate receptor ionotropic, NMDA ... 4 30
Sodium-dependent noradrenaline transporter and Sodium-dependen... 3 10
Dipeptidyl peptidase 4 Inhibitor N4-(4-chlorobenzyl)-2,4-diami... 10 22
Histamine H3 receptor Ligand N-benzyl-4-cyclopentylpiperazine-... 3 19
Dipeptidyl peptidase 4 Inhibitor 1-benzyl-4-(2,4-dichloropheny... 2 10
Calcium-activated potassium channel subunit alpha-1 Ligand N-m... 2 10
Sodium-dependent serotonin transporter Inhibitor 1-(2-(naphtha... 5 2
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 17 9
Aminopeptidase N Inhibitor N1-(4-chlorobenzyl)-2-benzyl-n3-hyd... 9 86
Sodium-dependent dopamine transporter and Sodium-dependent ser... 8 2
Sodium-dependent dopamine transporter and Sodium-dependent ser... 5 1
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-3'... 14 11
Bifunctional epoxide hydrolase 2 and Cytochrome P450 3A4 inhib... 4 13
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 7 9
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 2 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 12 0
D(1A) dopamine receptor and D(2) dopamine receptor ligand Sure... 2 0
Pyruvate kinase PKM and Huntingtin inhibitor CHEMBL1455935 family 1 3
Sigma non-opioid intracellular receptor 1 ligand 1-[2-(3,4-dic... 8 4
Transporter and Sodium-dependent dopamine transporter inhibito... 3 0
Transporter and Sodium-dependent serotonin transporter inhibit... 4 8
C-C chemokine receptor type 5 ligand N-[(1S)-3-[4-[[2-(2,4-dic... 4 9
Transporter and Sodium-dependent dopamine transporter inhibito... 6 1
Lysosomal Pro-X carboxypeptidase inhibitor (2S,3S)-2-[(2-amino... 3 3
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 8 4
Sodium-dependent serotonin transporter and Sodium-dependent no... 9 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 3 4
Sodium-dependent serotonin transporter and Sodium-dependent no... 3 3
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 4
Sodium-dependent noradrenaline transporter and Sodium-dependen... 2 12
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 3 1
D(1A) dopamine receptor and D(2) dopamine receptor ligand A314... 3 1
D(2) dopamine receptor and D(1A) dopamine receptor ligand AGN-... 2 1
Sigma non-opioid intracellular receptor 1 and 3-beta-hydroxyst... 1 1
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 2
Sodium-dependent dopamine transporter and Muscarinic acetylcho... 2 6
Nociceptin receptor and Mu-type opioid receptor ligand (1R,5R)... 4 9
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 4 1
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 2 1
Sodium-dependent dopamine transporter and Sodium-dependent nor... 1 0
Nociceptin receptor and Mu-type opioid receptor ligand 2-[2-[(... 1 0
Prostaglandin E synthase inhibitor AGN-PC-09QMEJ family 2 0
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 1 10
Cannabinoid receptor 1 ligand AGN-PC-078YV8 family 1 2
Nociceptin receptor and Mu-type opioid receptor ligand (NE)-N-... 1 0
Muscarinic acetylcholine receptor M2 and Muscarinic receptor 3... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00254783 DNC006313 Investigative Drug 2-(2-chlorophenyl)-2-morpholinoethanamine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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