CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1966
Family Name Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-aminobutyric acid receptor subunit beta-2 Ligand 6-ethyl-3-pentoxycarbonyl-4-quinolone Family
No. of Seeds 17 No. of Other Members 50
Family Centroid CFAMM00255973 Functional Category Investigative Drug with Natural Product
Superfamily Gamma-aminobutyric acid receptor subunit beta-2 and Gamma-aminobutyric acid receptor subunit alpha-1 Binder Superfamily
Class Class 2307

Cousin Family NamesSeedsMembers
DNA topoisomerase 2-beta and DNA topoisomerase 2-beta inhibito... 9 181
Sodium channel protein type 10 subunit alpha Ligand Tetracaine... 6 166
3-oxo-5-alpha-steroid 4-dehydrogenase 2 Inhibitor 4-[4-(benzyl... 2 19
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 2 1
Retinal dehydrogenase 1 and Menin inhibitor CHEMBL1507858 family 1 6
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 2 3
Muscarinic acetylcholine receptor M1 ligand 5-fluoro-4-oxo-1-[... 1 5
Casein kinase I isoform alpha inhibitor methyl (2Z)-3-oxo-2-(2... 1 0
5-hydroxytryptamine receptor 6 ligand AGN-PC-00ADLV family 1 0
Signal transducer and activator of transcription 3 inhibitor A... 2 1
2,4-dioxo-1-prop-2-enylquinoline-3-carboxylate NP ZINC02124992... 4 0
NP Methyl 3-acetyl-4-oxo-1,4-dihydroquinoline-8-carboxylate Fa... 2 0
2-methyl-6-oxo-1,2-dihydro-6H-pyrrolo[3,2,1-ij]quinoline-5-car... 3 0
3-[(Z)-3-chlorobut-2-enyl]-2-methyl-4-oxo-1H-quinoline-6-carbo... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00255974 DNC013006 Investigative Drug 6-ethyl-3-(2-methylbutoxycarbonyl)-4-quinolone
CFAMM00255967 DNC012999 Investigative Drug 3-ethoxycarbonyl-4-quinolone
CFAMM00255973 DNC013005 Investigative Drug 6-ethyl-3-pentoxycarbonyl-4-quinolone
CFAMM00255966 DNC012996 Investigative Drug GNF-PF-3645
CFAMM00255972 DNC013004 Investigative Drug 6-ethyl-3-(2-ethylbutoxycarbonyl)-4-quinolone
CFAMM00255965 DNC012997 Investigative Drug 3-ethoxycarbonyl-6-propyl-4-quinolone
CFAMM00255978 DNC013003 Investigative Drug 3-cyclopentoxycarbonyl-6-ethyl-4-quinolone
CFAMM00255931 DNC006399 Investigative Drug 6-ethyl-3-(3-methylbutoxycarbonyl)-4-quinolone
CFAMM00255964 DNC012994 Investigative Drug 3-ethoxycarbonyl-6-ethyl-2-methyl-4-quinolone
CFAMM00255977 DNC013002 Investigative Drug 6-ethyl-3-i-propoxycarbonyl-4-quinolone
CFAMM00255983 DNC013009 Investigative Drug GNF-PF-4421
CFAMM00255976 DNC013001 Investigative Drug 6-ethyl-3-(3-pentoxycarbonyl)-4-quinolone
CFAMM00255963 DNC012995 Investigative Drug 6-benzyl-3-propoxycarbonyl-4-quinolone
CFAMM00255929 DNC006400 Investigative Drug 6-benzyl-3-ethoxycarbonyl-4-quinolone
CFAMM00255982 DNC013008 Investigative Drug 6-ethyl-3-propoxycarbonyl-4-quinolone
CFAMM00255975 DNC013007 Investigative Drug 3-butoxycarbonyl-6-ethyl-4-quinolone
CFAMM00255968 DNC012998 Investigative Drug 3-butoxycarbonyl-4-quinolone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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