CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1970
Family Name Cytochrome P450 2D6 Inhibitor Bs 7840 Family
No. of Seeds 4 No. of Other Members 9
Family Centroid CFAMM00256029 Functional Category Investigative Drug
Superfamily Cytochrome P450 2D6 and Histone deacetylase 1 Binder Superfamily
Class Class 2309

Cousin Family NamesSeedsMembers
Opioid receptor ligand synthetic opioid methadone analog Dextr... 2 108
Histamine H1 receptor Ligand Terfenadine Family 3 50
Serotonin re-uptake Inhibitor Citalopram Family 6 4
Alpha adrenergic receptor Ligand Pseudoephedrine Family 4 96
Opioid receptor ligand opiate Levorphanol Family 18 537
Muscarinic acetylcholine receptor M1 Ligand Trihexyphenidyl Fa... 14 199
Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
Histamine H1 receptor Ligand Chlophedianol Family 4 46
Mu-type opioid receptor ligand opiate Methadyl Acetate Family 5 9
Nicotinic acetylcholine receptor Ligand Benztropine Mesylate F... 10 20
Noradrenergic re-uptake Inhibitor Desvenalfaxine Succinate Family 2 4
Eptazocine Hbr family 6 8
Noradrenergic re-uptake and Opioid receptor Ligand Tapentadol ... 21 79
Muscarinic acetylcholine receptor Ligand Umeclidinium Family 7 50
5-hydroxytryptamine receptor 1A Ligand (s)-uh-301 Family 35 20
Peptide deformylase, mitochondrial Inhibitor Hydroxamates Family 6 17
Fibroblast growth factor receptor Ligand SU5403 Family 8 8
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Sulfen... 5 13
Adenosine receptor A3 and D(2) dopamine receptor Ligand (+)-bu... 5 14
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
Oestrogen receptor and Estrogen receptor beta Ligand 6-(4-hydr... 30 63
Sodium-dependent dopamine transporter and Sodium-dependent nor... 9 16
Potassium voltage-gated channel subfamily A member 5 Ligand 2-... 3 1
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 7 19
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 11 3
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 5 14
Potassium voltage-gated channel subfamily H member 2 Ligand [1... 2 23
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 9 7
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 44 3
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-ri... 5 12
Sodium-dependent dopamine transporter and Sodium-dependent nor... 5 2
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 2 11
Sigma non-opioid intracellular receptor 1 ligand (1R)-1'-benzy... 7 27
Sigma non-opioid intracellular receptor 1 ligand 2-[(3R)-1'-(c... 2 0
Vesicular acetylcholine transporter inhibitor BENZOVESAMICOL f... 7 4
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 6 3
Vitamin D3 receptor ligand (3E,5E)-6-[3-[2-[3,4-bis(hydroxymet... 2 33
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 1 0
Squalene synthase inhibitor 3-[2-(4-phenylphenyl)ethynyl]-1-az... 2 1
Sodium-dependent dopamine transporter and Sodium-dependent ser... 1 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 1 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 4
Membrane primary amine oxidase and Amine oxidase [flavin-conta... 2 0
Dibenzocycloheptenes Metabolite E-10-Hydroxynortriptyline Family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00256037 CHEMBL597021 Bioactive AGN-PC-07RA0F
CFAMM00256029 DNC006408 Investigative Drug BS 7840

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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