CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1977
Family Name Oxysterols receptor LXR-alpha Ligand N-{4-[2-(4-methoxyphenyl)ethyl]phenyl}phthalimide Family
No. of Seeds 3 No. of Other Members 16
Family Centroid CFAMM00256174 Functional Category Investigative Drug with Natural Product
Superfamily Oxysterols receptor LXR-alpha Binder Superfamily
Class Class 2312

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
Acetylcholinesterase Inhibitor Donepezil Family 23 242
Dihydroorotate dehydrogenase and Interleukin-17A Inhibitor Vid... 4 74
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 18 12
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Amyloid beta A4 protein Inhibitor 6-iodo-4'-methylaminoflavone... 3 33
Histone deacetylase 2 Inhibitor N-(4-amino-3'-methoxybiphenyl-... 3 49
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Proto-oncogene tyrosine-protein kinase receptor Ret Ligand (z)... 1 60
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Tubulin beta chain Inhibitor Gnf-pf-117 Family 2 16
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 1 7
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 4
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 7 4
Sphingosine 1-phosphate receptor 1 ligand 2-methoxy-N-[(4-phen... 2 23
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 1 2
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 2 11
5-hydroxytryptamine receptor 1A ligand 3-hydroxy-6-iodo-2-[2-[... 2 0
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 1 2
Major prion protein and Microtubule-associated protein tau inh... 2 10
Beta-lactamase and Microtubule-associated protein tau inhibito... 1 1
N-(4-acetamidophenyl)-2-(2,2-dimethyl-3,4-dihydrochromen-6-yl)... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00256174 DNC009919 Investigative Drug N-{4-[2-(4-Methoxyphenyl)ethyl]phenyl}phthalimide
CFAMM00256167 DNC006424 Investigative Drug 2-(3-(benzyloxy)phenyl)isoindoline-1,3-dione
CFAMM00256182 DNC009920 Investigative Drug N-{4-[2-(3-Methoxyphenyl)ethyl]phenyl}phthalimide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26830 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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