CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1981
Family Name Sodium-dependent noradrenaline transporter Inhibitor (r)-1-((s)-morpholin-2-yl)-1,2-diphenylethanol Family
No. of Seeds 3 No. of Other Members 8
Family Centroid CFAMM00256339 Functional Category Investigative Drug
Superfamily Sodium-dependent noradrenaline transporter Inhibitor (r)-1-((s)-morpholin-2-yl)-1,2-diphenylethanol Superfamily
Class Class 89

Cousin Family NamesSeedsMembers
Alpha adrenergic receptor Ligand Pseudoephedrine Family 4 96
Alpha-2 adrenergic receptor ligand opiate Meperidine Family 13 76
Beta-1 adrenergic receptor Ligand Metoprolol Family 29 90
Muscarinic acetylcholine receptor Ligand Flutropium Bromide Fa... 6 45
Muscarinic acetylcholine receptor M2 ligand Tropane alkaloid S... 7 16
Muscarinic acetylcholine receptor M5 ligand Tropane alkaloid A... 18 12
Sodium channel protein type 5 subunit alpha Ligand Hexylcaine ... 4 94
Alpha-1B adrenergic receptor ligand Morpholine derivative Phen... 4 152
Muscarinic acetylcholine receptor M1 Ligand Trihexyphenidyl Fa... 14 199
Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
Muscarinic acetylcholine receptor Ligand Mepenzolate Family 35 11
Muscarinic acetylcholine receptor M1 Ligand Oxyphenonium Family 12 5
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
Cholinesterase Inhibitor 4-[4-(benzyloxy)piperidino]butyl-3-fl... 5 18
Potassium voltage-gated channel subfamily A member 5 Ligand 2-... 3 1
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 9 7
Sodium-dependent dopamine transporter and Sodium-dependent nor... 4 19
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 6 5
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 2 11
Sigma non-opioid intracellular receptor 1 ligand SureCN5315520... 3 11
Sigma non-opioid intracellular receptor 1 ligand methyl (1R,2S... 4 0
Glucosylceramidase inhibitor (2R,3S,4S,5R)-2-[2-(2-phenylethyl... 1 2
Transporter and Sodium-dependent serotonin transporter inhibit... 1 5
Sodium-dependent dopamine transporter and Sigma non-opioid int... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00256335 CHEMBL204574 Bioactive SureCN14202975
CFAMM00256334 CHEMBL141097 Bioactive 4-Piperidyl benzilate
CFAMM00256339 DNC006433 Investigative Drug (R)-1-((S)-morpholin-2-yl)-1,2-diphenylethanol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

38798 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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