CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID1995
Family Name Amyloid beta A4 protein Inhibitor 5-hydroxy-2-(4-methylaminophenyl)benzofuran Family
No. of Seeds 6 No. of Other Members 71
Family Centroid CFAMM00256731 Functional Category Investigative Drug with Natural Product
Superfamily Amyloid beta A4 protein Inhibitor 5-hydroxy-2-(4-methylaminophenyl)benzofuran Superfamily
Class Class 1685

Cousin Family NamesSeedsMembers
Amyloid beta A4 protein Inhibitor 6-iodo-4'-methylaminoflavone... 3 33
Platelet-derived growth factor receptor beta and Receptor-type... 1 3
Leukotriene A-4 hydrolase Inhibitor N5-[4-(2-oxo-3-phenylpropo... 1 61
Macrophage migration inhibitory factor Inhibitor Benzofuran-2-... 5 67
Gamma-aminobutyric acid receptor Ligand 2-(2-amino-phenyl)-6-m... 4 23
Sodium channel protein type 10 subunit alpha ligand AGN-PC-09M... 1 7
Thyroid hormone receptor beta and Microtubule-associated prote... 1 5
Progesterone receptor ligand AGN-PC-00PB7I family 1 5
Ras-related protein Rab-9A and Niemann-Pick C1 protein inhibit... 1 4


External ID

Functional Category

Molecule Name

CFAMM00256754 DNC006481 Investigative Drug 5-methoxy-2-(4-methylaminophenyl)benzofuran
CFAMM00256731 DNC006480 Investigative Drug 5-hydroxy-2-(4-methylaminophenyl)benzofuran
CFAMM00256774 DNC006475 Investigative Drug 5-methoxy-2-(4-aminophenyl)benzofuran
CFAMM00256729 DNC006482 Investigative Drug 5-hydroxy-2-(4-aminophenyl)benzofuran
CFAMM00256773 DNC006478 Investigative Drug 5-hydroxy-2-(4-dimethylaminophenyl)benzofuran
CFAMM00256772 DNC006479 Investigative Drug 5-methoxy-2-(4-dimethylaminophenyl)benzofuran

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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