CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2
Family Name 5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine receptor 2A Ligand 1192u90 Family
No. of Seeds 37 No. of Other Members 57
Family Centroid CFAMM00173555 Functional Category Investigative Drug
Superfamily 5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine receptor 2A Ligand 1192u90 Superfamily
Class Class 1106

Cousin Family NamesSeedsMembers
D(2) dopamine receptor ligand benzothiazolylpiperazine derivat... 6 56
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 1 0
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 18 11
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 2 13
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 10 0
Serine/threonine-protein kinase Chk1 inhibitor SureCN13010134 ... 7 29
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 3 1
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 8 12
Serine/threonine-protein kinase Chk1 inhibitor SureCN3070314 f... 16 32
Serine/threonine-protein kinase Chk1 inhibitor 2-(1-methylindo... 3 4
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 8 1
Cellular tumor antigen p53 and Prelamin-A/C inhibitor CHEMBL13... 1 2
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 9 1
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 1 0
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor lig... 2 5
5-hydroxytryptamine receptor 2A ligand AGN-PC-075XKY family 2 0
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor lig... 13 12
Serine/threonine-protein kinase Chk1 and Cyclin-dependent kina... 15 8
Orexin receptor type 2 and Orexin receptor type 1 ligand (2-me... 3 1
Glycogen synthase kinase-3 beta inhibitor N-[2-[4-(ethylsulfon... 2 2
5-hydroxytryptamine receptor 2A and Alpha-1A adrenergic recept... 13 1
5-hydroxytryptamine receptor 2A and Alpha-1A adrenergic recept... 7 0
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 17 0
Epidermal growth factor receptor and Vascular endothelial grow... 7 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 0
RAC-alpha serine/threonine-protein kinase and RAC-gamma serine... 20 7
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 2 0
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 2 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00173520 CHEMBL556030 Bioactive AGN-PC-07BYAB
CFAMM00173562 CHEMBL542058 Bioactive AGN-PC-07BYAI
CFAMM00173519 CHEMBL544909 Bioactive AGN-PC-07BYA4
CFAMM00173533 CHEMBL558192 Bioactive AGN-PC-07C1GY
CFAMM00173561 CHEMBL542059 Bioactive AGN-PC-07BYAJ
CFAMM00173577 CHEMBL142850 Bioactive SureCN9205690
CFAMM00173518 CHEMBL141438 Bioactive SureCN9210753
CFAMM00173532 CHEMBL314043 Bioactive 3-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-1,2,3-benzotriazin-4-one
CFAMM00173547 CHEMBL358268 Bioactive SureCN9272319
CFAMM00173566 CHEMBL554954 Bioactive AGN-PC-07BY9Z
CFAMM00173596 CHEMBL545143 Bioactive (2R)-2-[2-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butylcarbamoyl]anilino]-3-methylbutanoic acid;hydrochloride
CFAMM00173559 CHEMBL143075 Bioactive SureCN9210256
CFAMM00173552 CHEMBL553382 Bioactive AGN-PC-07BYA6
CFAMM00173581 CHEMBL537971 Bioactive AGN-PC-07C1JM
CFAMM00173588 CHEMBL538972 Bioactive AGN-PC-07C1IQ
CFAMM00173514 CHEMBL542554 Bioactive AGN-PC-07BYAO
CFAMM00173557 CHEMBL555303 Bioactive (2S)-2-[2-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butylcarbamoyl]anilino]-3-methylbutanoic acid;hydrochloride
CFAMM00173587 CHEMBL537700 Bioactive SureCN9381107
CFAMM00173555 DPR000003 Investigative Drug 1192U90

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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