CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2000
Family Name Protein kinase C eta type and Protein kinase C delta type Inhibitor 8-octyl-benzolactam-v9 Family
No. of Seeds 9 No. of Other Members 12
Family Centroid CFAMM00256887 Functional Category Investigative Drug
Superfamily Protein kinase C eta type and Protein kinase C delta type Inhibitor 8-octyl-benzolactam-v9 Superfamily
Class Class 348

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme Inhibitor Benazepril Family 7 123
Integrin alpha-4 Inhibitor BIO-1211 Family 16 83
Cyclophilin receptor and Cyclosporine receptor Ligand D-43787 ... 2 13
Cholecystokinin receptor type A Ligand VL-1499 Family 12 133
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Leukotriene A-4 hydrolase Inhibitor N5-[4-(n-phenylamino)pheny... 2 3
Sphingosine kinase 2 Inhibitor (r)-2-amino-4-hydroxy-n-(4-octy... 3 9
Leukotriene A-4 hydrolase Inhibitor SA-6541 Family 4 32
Prothrombin and Plasminogen inhibitor [(1R)-5-amino-1-[[2-[N-(... 1 0
Angiotensin-converting enzyme inhibitor AGN-PC-074KD3 family 2 0
Angiotensin-converting enzyme inhibitor (2R)-1-[4-carboxy-4-(p... 3 3
Protein kinase C alpha type inhibitor 5-[3,5-bis(trifluorometh... 3 0
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-2-[[(2S)-1... 6 6
Angiotensin-converting enzyme inhibitor (2S)-1-[(2S)-2-sulfany... 7 23
Pol polyprotein inhibitor Lysine Sulfonamide 11o family 2 6
Protein kinase C delta type and Protein kinase C alpha type in... 5 0
Mitogen-activated protein kinase 1 and M17 leucyl aminopeptida... 1 21
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 2 7
Stromelysin-1 inhibitor 6-(4'-FLUORO-BIPHENYL-4-YL)-4-(3-METHY... 3 0
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-1-... 3 3
Angiotensin-converting enzyme inhibitor (2S)-2-[[(3R)-5-(carbo... 6 4
Angiotensin-converting enzyme inhibitor 1-[(2R,4R)-4-carboxy-2... 2 3
Sodium channel protein type 9 subunit alpha ligand tert-butyl ... 2 30
Angiotensin-converting enzyme inhibitor 2-(N-[(2S)-6-amino-2-[... 2 1
Granzyme B and Caspase-3 inhibitor CHEMBL304368 family 2 1
Neprilysin and Angiotensin-converting enzyme inhibitor 3-[(3S)... 1 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 12 16


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00256866 CHEMBL120645 Bioactive CHEMBL120645
CFAMM00256872 CHEMBL351103 Bioactive (2S,5S)-5-(hydroxymethyl)-1-methyl-2-tetradecyl-2,4,5,6-tetrahydro-1,4-benzodiazocin-3-one
CFAMM00256879 CHEMBL28205 Bioactive (2S,5S)-8-decyl-5-(hydroxymethyl)-1-methyl-2-propan-2-yl-2,4,5,6-tetrahydro-1,4-benzodiazocin-3-one
CFAMM00256871 CHEMBL34971 Bioactive AC1L9TGE
CFAMM00256885 CHEMBL6453 Bioactive (2S,5S)-8-dec-1-ynyl-5-(hydroxymethyl)-1-methyl-2-propan-2-yl-2,4,5,6-tetrahydro-1,4-benzodiazocin-3-one
CFAMM00256870 CHEMBL159233 Bioactive (2S,5S)-2-decyl-5-(hydroxymethyl)-1-methyl-2,4,5,6-tetrahydro-1,4-benzodiazocin-3-one
CFAMM00256877 CHEMBL160375 Bioactive (2S,5S)-2-dodecyl-5-(hydroxymethyl)-1-methyl-2,4,5,6-tetrahydro-1,4-benzodiazocin-3-one
CFAMM00256869 CHEMBL37271 Bioactive (5S)-2-decyl-5-(hydroxymethyl)-1-methyl-2,4,5,6-tetrahydro-1,4-benzodiazocin-3-one
CFAMM00256887 DNC006485 Investigative Drug 8-Octyl-benzolactam-V9

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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