CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2001
Family Name Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 2-valproylamido-5-sulfonamidoindane Family
No. of Seeds 8 No. of Other Members 5
Family Centroid CFAMM00256894 Functional Category Investigative Drug
Superfamily Carbonic anhydrase 1 and Carbonic anhydrase 2 Binder Superfamily 9
Class Class 109

Cousin Family NamesSeedsMembers
SUR1-type K(ATP) channel and SUR2-type K(ATP) channel Ligand T... 3 35
ATP-sensitive inward rectifier potassium channel 10 Ligand Ace... 2 64
Cathepsin K Inhibitor Odanacatib Family 33 84
Suppressor of tumorigenicity 14 protein and Prothrombin Inhibi... 4 126
Thymidylate synthase Inhibitor N-[tosyl-d-prolinyl]amino-ethan... 1 10
Carbonic anhydrase 2 Inhibitor N-benzyl-4-sulfamoyl-benzamide ... 12 44
Neuromedin-K receptor Ligand PD-157672 Family 9 37
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 2-acet... 6 2
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 2-pent... 4 5
Cathepsin B and Cathepsin S Inhibitor Ac-hphe-leu-ala-leuvsme ... 17 51
Suppressor of tumorigenicity 14 protein Inhibitor 3-tapap Family 15 39
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-p... 6 19
Trypsin Inhibitor Benzamidrazone Analogue Family 16 6
5-hydroxytryptamine receptor 6 ligand N-[[(1R)-6-(benzenesulfo... 8 2
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 2 6
Cathepsin L1 and Cathepsin B inhibitor (2S)-3-methyl-N-[(2S)-4... 7 24
Pol polyprotein inhibitor Lysine Sulfonamide 11c family 3 73
Disintegrin and metalloproteinase domain-containing protein 17... 6 5
Matrix metalloproteinase-9 and Stromelysin-1 inhibitor N-[(2S)... 1 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 4
Carbonic anhydrase 12 and Carbonic anhydrase 2 inhibitor AGN-P... 5 0
Collagenase 3 and 72 kDa type IV collagenase inhibitor (2R)-N-... 10 1
Bifunctional epoxide hydrolase 2 inhibitor N-cycloheptyl-1-(2,... 7 8
Bifunctional epoxide hydrolase 2 inhibitor N-cycloheptyl-1-(2,... 1 0
B1 bradykinin receptor and B2 bradykinin receptor ligand SureC... 3 0
72 kDa type IV collagenase and Stromelysin-1 inhibitor (2R)-N-... 7 1
Neutrophil elastase inhibitor 1-[(2S)-3-methyl-2-(naphthalen-2... 3 1
72 kDa type IV collagenase and Stromelysin-1 inhibitor (3R)-3-... 3 2
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 1 1
Growth hormone secretagogue receptor type 1 ligand [(3S)-3-ami... 2 6
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor 2-[car... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00256889 CHEMBL185041 Bioactive AGN-PC-075GJX
CFAMM00256900 CHEMBL456889 Bioactive AGN-PC-04XI4K
CFAMM00256893 DNC006491 Investigative Drug 2-cyclohexylamido-5-sulfonamidoindane
CFAMM00256892 DNC006494 Investigative Drug 1-cyclohexylamido-5-sulfonamidoindane
CFAMM00256891 DNC006495 Investigative Drug 1-valproylamido-5-sulfonamidoindane
CFAMM00256901 DNC006487 Investigative Drug 2-butylamido-5-sulfonamidoindane
CFAMM00256896 DNC006486 Investigative Drug 2-nonylamido-5-sulfonamidoindane
CFAMM00256894 DNC006492 Investigative Drug 2-valproylamido-5-sulfonamidoindane

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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