CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2002
Family Name Aromatase Inhibitor 3-amino-4'-amino-trans-stilbene Family
No. of Seeds 5 No. of Other Members 47
Family Centroid CFAMM00256933 Functional Category Investigative Drug with Human Metabolite
Superfamily Aromatase and 5-hydroxytryptamine receptor 6 Binder Superfamily
Class Class 1960

Cousin Family NamesSeedsMembers
Noradrenergic re-uptake inhibitor Dibenzazepine Imipramine Family 8 178
D(2) dopamine receptor Ligand Nomifensine Family 6 100
Beta-lactamase Inhibitor M-aminophenylboronic Acid Family 2 16
Amiloride-sensitive amine oxidase [copper-containing] Inhibito... 1 5
5-hydroxytryptamine receptor 6 Ligand 4-(1h-inden-1-ylmethyl)-... 5 99
Potassium voltage-gated channel subfamily A member 3 Ligand CP... 4 26
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 14 78
Progesterone receptor Ligand 2,2,4-trimethyl-6-phenyl-1,2-dihy... 5 82
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 67
Transient receptor potential cation channel subfamily V member... 6 33
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 1 14
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor N-[4-(... 2 12
5-hydroxytryptamine receptor 6 Ligand N-(3-(2-aminoethyl)pheny... 8 25
Kinesin-like protein KIF11 Inhibitor N-(4'-chloro-4-biphenylyl... 1 2
Kinesin-like protein KIF11 Inhibitor N-[4'-(trifluoromethyl)-4... 3 13
Kinesin-like protein KIF11 Inhibitor N-[4'-(trifluoromethyl)-4... 2 9
Dipeptidyl peptidase 4 Inhibitor (3s,4r)-3-butyl-1-phenylpiper... 2 40
Histamine H3 receptor Ligand (r)-1-(4-nitrophenethyl)-2-methyl... 16 38
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 47
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 42
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 18
Amine oxidase [flavin-containing] B Inhibitor Methyl-(1,2,3,4-... 2 0
D(3) dopamine receptor and D(2) dopamine receptor ligand SureC... 1 4
Capsid scaffolding protein inhibitor 1,1,1-trifluoro-N-[5-[(E)... 3 1
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 1 12
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 2 4
Thyrotropin receptor and Cytochrome P450 3A4 ligand 2-Methyl-5... 1 10
Squalene monooxygenase inhibitor 3-[[[(E)-6,6-dimethylhept-2-e... 1 0
Acyl-CoA:cholesterol acyltransferase inhibitor N-[(1-phenylcyc... 1 0
Acenes Metabolite 1-Aminopyrene Family 1 63
3,3,5,5-tetramethyl-N-phenyl-1,2,4,6,7,8-hexahydronaphthalen-2... 2 0


External ID

Functional Category

Molecule Name

CFAMM00256939 CHEMBL15901 Bioactive BENZIDINE
CFAMM00256934 DNC010990 Investigative Drug 3,4'-(Ethane-1,2-diyl)dibenzenamine
CFAMM00256933 DNC010991 Investigative Drug 3-Amino-4'-amino-trans-stilbene
CFAMM00256914 DNC010992 Investigative Drug 3,5-Diamino-4'-amino-trans-stilbene
CFAMM00256925 DNC006514 Investigative Drug 1,6-bis(4'-aminophenyl)-hexa-1,3,5-triene

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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