CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2004
Family Name Glutamate carboxypeptidase 2 Inhibitor 2-(3-carboxybenzyl)succinic Acid Family
No. of Seeds 2 No. of Other Members 7
Family Centroid CFAMM00257027 Functional Category Investigative Drug
Superfamily Glutamate carboxypeptidase 2 and Beta-lactamase Binder Superfamily
Class Class 1688

Cousin Family NamesSeedsMembers
Retinoid X receptor Ligand Bexarotene Family 7 492
Cyclooxygenase Inhibitor Flurbiprofen Family 18 294
Prostaglandin G/H synthase 2 Inhibitor Ketoprofen Family 5 84
DNA topoisomerase 2-beta Inhibitor Salvicine Family 2 9
Carbonic anhydrase 2 Inhibitor 4-(hydroxymercury)benzoic Acid ... 7 97
Nicotinate-nucleotide pyrophosphorylase [carboxylating] Inhibi... 2 119
Beta-lactamase Inhibitor 4-carboxyphenylboronic Acid Family 1 1
Carboxypeptidase B2 Inhibitor Dl-benzylsuccinic Acid Family 1 11
C-X-C chemokine receptor type 1 and C-X-C chemokine receptor t... 2 53
Liver carboxylesterase 1 Inhibitor 1,2-bis(2,5-difluorophenyl)... 12 10
72 kDa type IV collagenase and Macrophage metalloelastase Inhi... 2 5
Glutamate carboxypeptidase 2 Inhibitor 2-(3-carbamoylbenzyl)-5... 2 1
Glutamate carboxypeptidase 2 Inhibitor 3-(2-carboxy-6-mercapto... 9 4
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-(6-hydroxy-2-nap... 7 9
Arachidonate 12-lipoxygenase, 12S-type and Arachidonate 15-lip... 3 7
Protein kinase C delta type and Protein kinase C alpha type In... 4 105
Fatty-acid amide hydrolase 1 Inhibitor 3-(ethoxycarbonyl)pheny... 2 69
Glutamate carboxypeptidase 2 inhibitor SureCN5052894 family 1 17
Arachidonate 15-lipoxygenase inhibitor SureCN9469035 family 6 40
DNA-(apurinic or apyrimidinic site) lyase and Retinal dehydrog... 1 18
Integrase inhibitor AGN-PC-00QHSA family 1 2
Indanes Metabolite (R)-Pterosin B Family 5 8
(1S)-1-hydroxy-1,4-dimethyl-2,3-dihydrocyclopenta[b]anthracene... 1 1
carboxylate NP ZINC04026424 Family 3 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00257030 DNC006519 Investigative Drug 3-(2-carboxy-3-phosphonopropyl)benzoic acid
CFAMM00257027 DNC006518 Investigative Drug 2-(3-carboxybenzyl)succinic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

67935 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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