CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2011
Family Name Inhibitor of nuclear factor kappa-B kinase subunit beta Inhibitor 3-amino-benzo[b]thiophene-2-carboxylic Acid Amide Family
No. of Seeds 2 No. of Other Members 5
Family Centroid CFAMM00257073 Functional Category Investigative Drug
Superfamily Binder Superfamily 9
Class Class 2206

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase Chk1 Inhibitor AZD7762 Family 26 90
Adenosine receptor A2a Ligand T-62 Family 1 4
Adenosine receptor A1 Ligand PD-81723 Family 1 2
Inhibitor of nuclear factor kappa-B kinase subunit beta Inhibi... 2 0
Serine/threonine-protein kinase Chk1 inhibitor AGN-PC-09M88E f... 1 7
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 0
Survival motor neuron protein and Nuclear receptor ROR-gamma l... 1 2
Flap endonuclease 1 and DNA repair protein complementing XP-G ... 4 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-speci... 1 11
Serine/threonine-protein kinase pim-3 and Serine/threonine-pro... 16 11
ATP-dependent DNA helicase Q1 and Menin inhibitor 77651-38-8 f... 1 0
Arachidonate 15-lipoxygenase and Nonstructural protein 1 inhib... 1 0


External ID

Functional Category

Molecule Name

CFAMM00257074 DNC006550 Investigative Drug 2-amino-5-phenylthiophene-3-carboxamide
CFAMM00257073 DNC006548 Investigative Drug 3-amino-benzo[b]thiophene-2-carboxylic acid amide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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