CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2018
Family Name C-C chemokine receptor type 4 Ligand N-(naphthalen-1-yl)-4-neopentylthiazol-2-amine Family
No. of Seeds 5 No. of Other Members 78
Family Centroid CFAMM00257317 Functional Category Investigative Drug
Superfamily C-C chemokine receptor type 4 Binder Superfamily
Class Class 2319

Cousin Family NamesSeedsMembers
Cytochrome P450 26A1 Inhibitor Rambazole Family 7 77
A-623 family 2 3
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-me... 2 45
Metabotropic glutamate receptor 5 Ligand N-[4-(3-pyridylethyny... 2 10
C-C chemokine receptor type 4 Ligand N-(4-tert-butylthiazol-2-... 3 9
C-C chemokine receptor type 4 Ligand 4-tert-butyl-n-o-tolylthi... 4 7
Histone deacetylase 1 and Histone deacetylase 4 Inhibitor 7-me... 3 14
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 20 26
Cyclin-dependent kinase 5 Inhibitor 1-phenyl-3-(2-(pyridin-4-y... 3 53
Adenosine receptor A1 Ligand N-(4-phenyl-thiazol-2-yl)-benzami... 5 2
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-264... 6 32
Amine oxidase [flavin-containing] B Inhibitor 2-(2-cyclohexyli... 6 44
Reverse transcriptase Inhibitor PT-316 Family 8 2
Reverse transcriptase Inhibitor 1-benzothiazol-2-yl-3-phenethy... 2 19
Neuropeptide Y receptor type 5 ligand N-[[(1S,5R)-3-(1-phenyle... 5 1
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 2 8
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 8
Amine oxidase [flavin-containing] B inhibitor 4-(4-fluoropheny... 3 4
Platelet-activating factor receptor ligand Foropafant family 2 0
Neuropeptide Y receptor type 5 ligand N-[5-(4,5-dihydro-[1]ben... 8 9
Neuropeptide Y receptor type 5 ligand N-[5-[(9-fluoro-5,6-dihy... 7 7
Neuropeptide Y receptor type 5 ligand N-[5-[(4-thiophen-3-yl-1... 1 4
Mitogen-activated protein kinase 14 inhibitor N-[4-[2-ETHYL-4-... 4 5
Cholinesterase and Acetylcholinesterase inhibitor 3-[ethyl-[3-... 6 9
Vascular endothelial growth factor receptor 2 ligand N-(1,3-Th... 4 4
Bifunctional epoxide hydrolase 2 inhibitor 1-(1-adamantyl)-3-(... 1 0
Methionine aminopeptidase 2 inhibitor SureCN5371860 family 3 0
Neuropeptide Y receptor type 5 ligand 1-[4-[[(9-fluoro-5,6-dih... 11 0
Mitogen-activated protein kinase 14 inhibitor 303163-37-3 family 1 2
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... 4 1
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 2 4
Proto-oncogene tyrosine-protein kinase LCK and Tyrosine-protei... 3 9
Kynurenine 3-monooxygenase inhibitor 4-amino-N-[4-(3-nitrophen... 2 2
Membrane primary amine oxidase inhibitor N-[4-[2-[4-(diaminome... 5 0
Fructose-1,6-bisphosphatase 1 inhibitor AGN-PC-079IZF family 1 3
Beta-lactamase and Microtubule-associated protein tau inhibito... 1 0
Histamine H2 receptor ligand 2-[4-[3-[[4-(methylamino)-1-oxo-1... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00257323 DNC006588 Investigative Drug 4-tert-butyl-N-(naphthalen-1-yl)thiazol-2-amine
CFAMM00257322 DNC006589 Investigative Drug 4-isopropyl-N-(naphthalen-1-yl)thiazol-2-amine
CFAMM00257318 DNC006586 Investigative Drug N-(naphthalen-1-yl)-4-phenylthiazol-2-amine
CFAMM00257317 DNC006587 Investigative Drug N-(naphthalen-1-yl)-4-neopentylthiazol-2-amine
CFAMM00257365 DNC006577 Investigative Drug 4-methyl-N-(naphthalen-1-yl)thiazol-2-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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