CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2021
Family Name C-C chemokine receptor type 4 Ligand 4-tert-butyl-n-o-tolylthiazol-2-amine Family
No. of Seeds 4 No. of Other Members 7
Family Centroid CFAMM00257432 Functional Category Investigative Drug
Superfamily C-C chemokine receptor type 4 Binder Superfamily
Class Class 2319

Cousin Family NamesSeedsMembers
A-623 family 2 3
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-me... 2 45
C-C chemokine receptor type 4 Ligand N-(naphthalen-1-yl)-4-neo... 5 78
C-C chemokine receptor type 4 Ligand N-(4-tert-butylthiazol-2-... 3 9
Histone deacetylase 1 and Histone deacetylase 4 Inhibitor 7-me... 3 14
Nitric oxide synthase, brain and Nitric oxide synthase, endoth... 2 11
Adenosine receptor A1 Ligand N-(4-phenyl-thiazol-2-yl)-benzami... 5 2
Reverse transcriptase Inhibitor PT-316 Family 8 2
Reverse transcriptase Inhibitor LY-73497 Family 14 5
Reverse transcriptase Inhibitor 1-benzothiazol-2-yl-3-phenethy... 2 19
Histone deacetylase 1 and Histone deacetylase 2 inhibitor AGN-... 2 5
Bifunctional epoxide hydrolase 2 inhibitor 1-(1-adamantyl)-3-(... 1 0
Methionine aminopeptidase 2 inhibitor SureCN5371860 family 3 0
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 5 0
Membrane primary amine oxidase inhibitor N-[4-[2-[4-(diaminome... 5 0
Beta-lactamase and Microtubule-associated protein tau inhibito... 1 0
Long-chain fatty acid transport protein 1 inhibitor N-(4,5-dim... 2 0
Histamine H2 receptor ligand 2-[4-[3-[[4-(methylamino)-1-oxo-1... 1 0


External ID

Functional Category

Molecule Name

CFAMM00257434 DNC006582 Investigative Drug 4-tert-butyl-N-(2-isopropylphenyl)thiazol-2-amine
CFAMM00257433 DNC006583 Investigative Drug 4-tert-butyl-N-m-tolylthiazol-2-amine
CFAMM00257432 DNC006584 Investigative Drug 4-tert-butyl-N-o-tolylthiazol-2-amine
CFAMM00257431 DNC006585 Investigative Drug 4-tert-butyl-N-phenylthiazol-2-amine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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