CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2033
Family Name Proto-oncogene tyrosine-protein kinase Src Inhibitor Ac-cys-ile-phe(4-no2)-lys-tyr-phe(4-no2) Family
No. of Seeds 9 No. of Other Members 43
Family Centroid CFAMM00257650 Functional Category Investigative Drug with Natural Product
Superfamily Kappa-type opioid receptor and Delta-type opioid receptor Binder Superfamily 4
Class Class 18

Cousin Family NamesSeedsMembers
Vasopressin V2 receptor ligand peptide analog Desmopressin family 111 1472
Trypsin inhibitor polypeptide Aprotinin Family 7 68
Oxytocin receptor Ligand Oxytocin Family 30 182
Glucan synthesis regulatory protein Inhibitor Caspofungin Family 17 71
Glycoprotein IIb/IIIa receptor Ligand Tirofiban Family 4 173
Growth hormone-releasing hormone receptor ligand polypeptide ... 14 34
Mu-type opioid receptor Ligand Alvimopan Family 32 325
Thymopentin family 20 133
Neuropeptide Y receptor type 1 Ligand Bibp 3226 Family 43 80
Vasopeptidase Inhibitor Sampatrilat Family 25 9
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 20 35
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Proto-oncogene tyrosine-protein kinase Src Inhibitor Glu-pro-g... 8 4
Proto-oncogene tyrosine-protein kinase Src Inhibitor Y-c[d-pen... 20 66
Proto-oncogene tyrosine-protein kinase Src Inhibitor Ac-cys-il... 36 12
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 12 46
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 23 9
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 36 15
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 31 5
Mu-type opioid receptor and Nociceptin receptor Ligand Ac-ryyr... 60 11
C-X-C chemokine receptor type 4 Ligand Cyclo(-d-tyr-l-ala-l-ar... 25 23
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 49 19
Mu-type opioid receptor Ligand H-tyr-d-ala-aic-asp-val-val-gly... 48 8
Genome polyprotein Inhibitor Acasp-glu-dif-ile-cha-cys-iqc-nle... 9 0
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 152 36
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 11 4
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 8 4
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 48 10
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 95 46
Neprilysin and Angiotensin-converting enzyme inhibitor AGN-PC-... 3 7
Vasopressin V1a receptor ligand (10S,13S,16S,19S,22S)-N-[(2S)-... 1 0
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-1-... 3 3
Oxytocin receptor ligand (2S)-N-[(2R)-1-[2-[[5-amino-1-[[1-ami... 4 0
Angiotensin-converting enzyme and Neprilysin inhibitor (2S,5R)... 15 3
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 2 0
Neurotensin receptor type 1 ligand (2S)-2-[[(2S,3S)-2-[[(2S)-2... 2 1
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 1 0
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 2 0
Angiotensin-converting enzyme 2 and Neprilysin inhibitor (2S)-... 6 1
D(4) dopamine receptor ligand 1-Piperidineacetamide, 4-(3-hydr... 1 0
Somatostatin receptor type 2 ligand CHEMBL526524 family 3 0
Somatostatin receptor type 2 and Somatostatin receptor type 3 ... 2 0
IgG receptor FcRn large subunit p51 ligand (4S,7S,16S,22S,25R,... 2 0
Integrin alpha-3 inhibitor 2-[(6S,12R,15R,20R,23S,26S,28R)-15-... 2 1
Prothrombin inhibitor (2S)-2-[[(2R)-2-[[(2S)-2-[[(2R)-2-[[(2S)... 2 0
Matrix metalloproteinase-9 and Metalloproteinase inhibitor 3 i... 6 2
Matrix metalloproteinase-9 and Metalloproteinase inhibitor 3 i... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00257650 DNC006628 Investigative Drug Ac-Cys-Ile-Phe(4-NO2)-Lys-Tyr-Phe(4-NO2)
CFAMM00257654 DNC006621 Investigative Drug Cyclo[Ac-Cys-Ile-Tyr-Lys-Tyr-Phe]
CFAMM00257683 DNC006622 Investigative Drug Cyclo[Ac-Cys-Ile-Phe]-Lys-Tyr-Tyr
CFAMM00257640 DNC006632 Investigative Drug Ac-Cys-Ile-Phe(4-NO2)-Lys-Tyr-Tyr
CFAMM00257646 DNC006629 Investigative Drug Ac-Cys-Ile-Tyr-Lys-Phe(4-NO2)-Phe(4-NO2)
CFAMM00257639 DNC006630 Investigative Drug Ac-Cys-Ile-Phe(4-NO2)-Lys-Phe(4-NO2)-Tyr
CFAMM00257652 DNC006624 Investigative Drug Ac-Cys-Ile-Tyr-Lys-Phe(4-N3)-Tyr
CFAMM00257638 DNC006631 Investigative Drug Ac-Cys-Ile-Tyr-Lys-Tyr-Phe(4-NO2)
CFAMM00257651 DNC006627 Investigative Drug Ac-Cys-Ile-Tyr-Lys-Phe(4-NO2)-Tyr-Phe

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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