CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2042
Family Name Tyrosine-protein phosphatase non-receptor type 1 Ligand Caulerpin Family
No. of Seeds 2 No. of Other Members 8
Family Centroid CFAMM00257867 Functional Category Investigative Drug
Superfamily Tubulin beta chain and Kinesin-like protein KIF11 Binder Superfamily
Class Class 247

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Dolasetron Family 12 171
Prostaglandin G/H synthase 2 Inhibitor Carprofen Family 1 5
Indoleamine 2,3-dioxygenase 1 Inhibitor L-tryptophan Family 8 328
Dihydroorotate dehydrogenase Inhibitor Brequinar Family 9 122
AP endonuclease APE1 Inhibitor 5-fluoro-1h-indole-2-carboxylic... 2 61
Cannabinoid receptor 2 Ligand JWH-202 Family 9 172
Lethal factor Inhibitor 3-(2,5-dimethyl-1h-pyrrol-1-yl)benzoic... 2 44
Serine/threonine-protein kinase Chk1 and Wee1-like protein kin... 2 101
Fatty acid-binding protein, adipocyte Inhibitor 1-benzyl-2,3-d... 1 8
Arachidonate 5-lipoxygenase Inhibitor Methyl 2-(benzylamino)-1... 3 10
Kinesin-like protein KIF11 Inhibitor Methyl 7-tert-butyl-9h-ca... 2 9
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 24 64
Tubulin beta chain Inhibitor Isopropyl 3-(phenylthio)-1h-indol... 1 7
Sodium-dependent serotonin transporter and D(2) dopamine recep... 13 2
NS5B protein inhibitor AC1NQMYG family 6 12
Retinoic acid receptor alpha and Retinoic acid receptor beta l... 1 2
NS5B protein inhibitor AGN-PC-00A17Z family 1 23
NS5B protein inhibitor AC1NQMYP family 5 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand SureC... 1 3
Gonadotropin-releasing hormone receptor ligand SureCN7997217 f... 3 1
Peroxisome proliferator-activated receptor gamma ligand AGN-PC... 4 4
Muscarinic acetylcholine receptor M1 and Cytochrome P450 2C19 ... 1 4
Thrombopoietin receptor ligand AGN-PC-077M9L family 2 4
Serine/threonine-protein kinase pim-3 inhibitor methyl 6-amino... 1 2
Indoles Metabolite 7-Hydroxyheptaphylline Family 4 0
Indoles Metabolite Mukeic acid Family 1 1
2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-2-ium-8-carboxylate N... 2 0
8-carbamoyl-6,7,8,9-tetrahydro-5H-carbazole-1-carboxylate NP Z... 2 0


External ID

Functional Category

Molecule Name

CFAMM00257867 DNC006667 Investigative Drug CAULERPIN
CFAMM00257865 DNC011010 Investigative Drug methyl 9H-carbazole-2-carboxylate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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