CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID206
Family Name Arachidonate 5-lipoxygenase Inhibitor Bw A4C Family
No. of Seeds 3 No. of Other Members 18
Family Centroid CFAMM00184208 Functional Category Investigative Drug
Superfamily Arachidonate 5-lipoxygenase Binder Superfamily
Class Class 1466

Cousin Family NamesSeedsMembers
Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Serine/threonine-protein kinase PLK1 Inhibitor On 019190.na Fa... 16 138
Melatonin receptor type 1A Ligand Agomelatine Family 12 164
5-hydroxytryptamine receptor 2A Ligand Pimavanserin Family 4 23
Arachidonate 5-lipoxygenase Inhibitor Bw B70C Family 2 36
Histamine H3 receptor Ligand UCL-2138 Family 23 172
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
Fatty-acid amide hydrolase 1 Inhibitor 3-(trifluoromethyl)phen... 3 0
Arachidonate 5-lipoxygenase Inhibitor 2-(4-butoxy-phenyl)-n-hy... 3 9
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 1 0
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 3 14
Metabotropic glutamate receptor 2 ligand (5R)-3-[[4-(4-ethoxyp... 3 9
Dehydrosqualene synthase and Squalene synthase inhibitor dipot... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00184208 DNC000364 Investigative Drug BW A4C
CFAMM00184207 DNC000365 Investigative Drug BW B218C
CFAMM00184227 DNC009729 Investigative Drug (N-(3-phenoxycinnamyl)-acetohydroxamic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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