CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2062
Family Name Gamma-secretase subunit APH-1B and Presenilin-1 Inhibitor (5r,6s)-6-(benzyloxy)-5-methoxycyclohex-2-enone Family
No. of Seeds 3 No. of Other Members 9
Family Centroid CFAMM00258503 Functional Category Investigative Drug with Human Metabolite
Superfamily Presenilin-1 and Liver carboxylesterase 1 Binder Superfamily
Class Class 2216

Cousin Family NamesSeedsMembers
DNA topoisomerase 1 Inhibitor Beta-lapachone Family 3 66
Nicotinate-nucleotide pyrophosphorylase [carboxylating] Inhibi... 2 119
Liver carboxylesterase 1 Inhibitor 1,2-bis(2,5-difluorophenyl)... 12 10
Liver carboxylesterase 1 Inhibitor 2,2-dimethoxy-1,2-diphenyl-... 1 16
Fatty-acid amide hydrolase 1 Inhibitor 3-(ethoxycarbonyl)pheny... 2 69
Cellular tumor antigen p53 and Thyrotropin receptor ligand CHE... 1 19
Benzyloxycarbonyls Metabolite Benzyl acetate Family 5 53
Epoxides Metabolite Phenylmethylglycidic ester Family 2 17
Benzyloxycarbonyls Metabolite Benzyl acetoacetate Family 1 6
3-methyl-1-oxo-4H-isochromene-3-carboxylate NP Methyl 3-methyl... 4 1
methylbenzoate NP 7-oxocyclohepta-1,3,5-trien-1-yl 3-methylben... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00258497 DNC006737 Investigative Drug (2S,3R)-2-(benzyloxy)-3-methoxycyclohexanone
CFAMM00258503 DNC006742 Investigative Drug (5R,6S)-6-(benzyloxy)-5-methoxycyclohex-2-enone
CFAMM00258502 DNC006741 Investigative Drug (5R,6S)-5,6-bis(benzyloxy)cyclohex-2-enone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

39828 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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