CFAM

Seed Molecules
Non-seed Members

CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00258819 CHEMBL104731 Bioactive 3-[(2R)-3-(4-methylpiperidin-1-yl)-2-(naphthalen-2-ylsulfonylamino)-3-oxopropyl]benzenecarboximidamide
CFAMM00258818 CHEMBL7656 Bioactive (2S)-3-(4-carbamimidoylphenyl)-N-cyclopentyl-N-methyl-2-(naphthalen-2-ylsulfonylamino)propanamide
CFAMM00258823 CHEMBL46842 Bioactive (2S)-3-(4-carbamimidoylphenyl)-N-cyclopentyl-N-methyl-2-[(4-propylphenyl)sulfonylamino]propanamide
CFAMM00258816 CHEMBL162216 Bioactive 4-[3-[(3S)-3-(benzenesulfonamido)-2-oxoazepan-1-yl]-2-oxopropyl]benzenecarboximidamide
CFAMM00258835 DNC006761 Investigative Drug 3-tapap

CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00258833 CHEMBL298013 Bioactive (2S)-3-(5-carbamimidoylthiophen-2-yl)-N-cyclopentyl-N-methyl-2-(naphthalen-2-ylsulfonylamino)propanamide
CFAMM00258844 CHEMBL512118 Bioactive 3-[(2S)-3-[4-(2-aminoethyl)piperidin-1-yl]-2-[[3-(3-aminopropylamino)phenyl]sulfonylamino]-3-oxopropyl]benzenecarboximidamide
CFAMM00258811 CHEMBL48133 Bioactive (2S)-3-(5-carbamimidoylthiophen-2-yl)-N-cyclopentyl-N-methyl-2-[(4-propylphenyl)sulfonylamino]propanamide
CFAMM00258815 CHEMBL110628 Bioactive AC1NFSTC
CFAMM00258828 CHEMBL107203 Bioactive AGN-PC-074VYB
CFAMM00258808 CHEMBL135041 Bioactive AGN-PC-00NUUH
CFAMM00258821 CHEMBL320285 Bioactive AGN-PC-074VXX
CFAMM00258847 CHEMBL348266 Bioactive AGN-PC-075SEB
CFAMM00258834 CHEMBL135815 Bioactive ethyl 3-(4-carbamimidoylphenyl)-2-[[2-[(4-carbamimidoylphenyl)sulfonylamino]acetyl]amino]propanoate
CFAMM00258814 CHEMBL108058 Bioactive AGN-PC-074VXA
CFAMM00258827 CHEMBL211549 Bioactive 3-[(2S)-3-[4-[3-(diaminomethylideneamino)propanoyl]piperazin-1-yl]-2-(2-naphthalen-1-ylethylsulfonylamino)-3-oxopropyl]benzenecarboximidamide
CFAMM00258846 CHEMBL104930 Bioactive 3-[2-(benzenesulfonamido)-3-(4-methylsulfonylpiperazin-1-yl)-3-oxopropyl]benzenecarboximidamide
CFAMM00258806 CHEMBL106395 Bioactive AGN-PC-074VXQ
CFAMM00258832 CHEMBL105875 Bioactive AGN-PC-074VXP
CFAMM00258838 CHEMBL352587 Bioactive 2-[5-(4-ethylpiperidin-1-yl)-4-[(6-methylnaphthalen-2-yl)sulfonylamino]-5-oxopentyl]guanidine
CFAMM00258805 CHEMBL208586 Bioactive 3-[(2S)-3-oxo-3-[4-(piperidine-4-carbonyl)-1,4-diazepan-1-yl]-2-[[2,4,6-tri(propan-2-yl)phenyl]sulfonylamino]propyl]benzenecarboximidamide
CFAMM00258837 CHEMBL423699 Bioactive AGN-PC-00NUUG
CFAMM00258817 CHEMBL209334 Bioactive 3-[(2S)-3-[4-[3-(diaminomethylideneamino)propanoyl]piperazin-1-yl]-2-(naphthalen-2-ylmethylsulfonylamino)-3-oxopropyl]benzenecarboximidamide
CFAMM00258843 CHEMBL461440 Bioactive N-[3-[[(2S)-1-[4-(2-aminoethyl)piperidin-1-yl]-3-(3-carbamimidoylphenyl)-1-oxopropan-2-yl]sulfamoyl]phenyl]propanamide
CFAMM00258829 CHEMBL169050 Bioactive 2-[5-(4-ethylpiperidin-1-yl)-4-[(7-methylnaphthalen-2-yl)sulfonylamino]-5-oxopentyl]guanidine
CFAMM00258842 CHEMBL137780 Bioactive ethyl 3-(3-carbamimidoylphenyl)-2-[[2-[(4-carbamimidoylphenyl)sulfonylamino]acetyl]amino]propanoate
CFAMM00258809 CHEMBL168805 Bioactive 2-[4-[(6-ethylnaphthalen-2-yl)sulfonylamino]-5-(4-ethylpiperidin-1-yl)-5-oxopentyl]guanidine
CFAMM00258822 CHEMBL211401 Bioactive 3-amino-N-[4-[[(2S)-1-[4-(2-aminoethyl)piperidin-1-yl]-3-(3-carbamimidoylphenyl)-1-oxopropan-2-yl]sulfamoyl]phenyl]propanamide
CFAMM00258841 CHEMBL438959 Bioactive 4-[4-[(2S)-3-(3-carbamimidoylphenyl)-2-[[2,4,6-tri(propan-2-yl)phenyl]sulfonylamino]propanoyl]-1,4-diazepane-1-carbonyl]piperidine-1-carboximidamide
CFAMM00258807 CHEMBL9461 Bioactive N-[(2S)-3-[4-[amino(hydrazinyl)methyl]phenyl]-1-(4-methylsulfonylpiperazin-1-yl)-1-oxopropan-2-yl]naphthalene-2-sulfonamide
CFAMM00258826 CHEMBL356067 Bioactive AGN-PC-075OVU
CFAMM00258839 CHEMBL319035 Bioactive 3-[(2R)-2-[2-(7,7-dimethyl-3-oxo-4-bicyclo[2.2.1]heptanyl)ethylsulfonylamino]-3-(4-methylsulfonylpiperazin-1-yl)-3-oxopropyl]benzenecarboximidamide
CFAMM00258813 CHEMBL318177 Bioactive AGN-PC-074V1B
CFAMM00258845 CHEMBL379586 Bioactive (S)-4-(4-(3-(3-CARBAMIMIDOYLPHENYL)-2-(2,4,6-TRIISOPROPYLPHENYLSULFONAMIDO)PROPANOYL)PIPERAZINE-1-CARBONYL)PIPERIDINE-1-CARBOXIMIDAMIDE
CFAMM00258812 CHEMBL498394 Bioactive AGN-PC-04UWTJ
CFAMM00258825 CHEMBL212577 Bioactive 2-amino-N-[3-[[(2S)-1-[4-(2-aminoethyl)piperidin-1-yl]-3-(3-carbamimidoylphenyl)-1-oxopropan-2-yl]sulfamoyl]phenyl]acetamide
CFAMM00258831 CHEMBL464247 Bioactive N-[[2-[4-[[(3R,5S)-3,5-dimethylpiperazin-1-yl]methyl]phenyl]phenyl]methyl]-N-methyl-2-[(4-methylphenyl)sulfonylamino]acetamide
CFAMM00258824 CHEMBL209963 Bioactive 3-[(2S)-3-[4-(3-aminopropanoyl)-1,4-diazepan-1-yl]-3-oxo-2-[[2,4,6-tri(propan-2-yl)phenyl]sulfonylamino]propyl]benzenecarboximidamide
CFAMM00258804 CHEMBL209910 Bioactive 3-[(2S)-3-[4-[3-(diaminomethylideneamino)propanoyl]-1,4-diazepan-1-yl]-3-oxo-2-[[2,4,6-tri(propan-2-yl)phenyl]sulfonylamino]propyl]benzenecarboximidamide
CFAMM00258830 CHEMBL544830 Bioactive (2R)-N-[[(3S)-1-carbamimidoylpiperidin-3-yl]methyl]-2-(naphthalen-2-ylsulfonylamino)-3-phenylpropanamide;hydrochloride
CFAMM00258810 CHEMBL492342 Bioactive SureCN8201054
CFAMM00258836 CHEMBL539047 Bioactive (2R)-N-[(1-carbamimidoylpiperidin-3-yl)methyl]-2-(naphthalen-2-ylsulfonylamino)-3-phenylpropanamide;hydrochloride
CFAMM00258840 18382273 Patent Compound AGN-PC-01VA8A
CFAMM00258820 57259105 Patent Compound AGN-PC-0BQI80

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by

2014.08.29