CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2078
Family Name Delta-type opioid receptor and Kappa-type opioid receptor Ligand MC-CAM Family
No. of Seeds 32 No. of Other Members 30
Family Centroid CFAMM00259096 Functional Category Investigative Drug
Superfamily Delta-type opioid receptor and Kappa-type opioid receptor Ligand MC-CAM Superfamily
Class Class 727

Cousin Family NamesSeedsMembers
u-type opioid receptor ligand opiate analog Buprenorphine Family 78 234
u-type opioid receptor ligand opiate opiate analog Oxymorphone... 22 105
Nalfurafine Hcl family 33 107
Mu-type opioid receptor Ligand Cyprodime Family 12 8
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 6 1
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 16 10
Kappa-type opioid receptor Ligand Morphinan Cyclic Imine Analo... 20 0
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 13 5
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 3 0
Mu-type opioid receptor ligand Morphine-6-glucuronide family 7 1
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 3 0
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 6 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 18 1
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 3 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 9 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 6 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 7 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 9 2
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 6 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 6 3
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 8 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 7 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 10 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 1 2
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 1 0
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00259084 CHEMBL385482 Bioactive (4R,4aS,7aR,12bR)-4a-[[(E)-3-(4-chlorophenyl)prop-2-enyl]amino]-3-(cyclopropylmethyl)-9-hydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one
CFAMM00259062 CHEMBL574397 Bioactive N-[(4R,4aS,7aR,12bR)-3-(cyclopropylmethyl)-9-hydroxy-7-oxo-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl]-3-(4-chlorophenyl)prop-2-ynamide
CFAMM00259076 CHEMBL610286 Bioactive methyl 2-[[(4R,4aS,7aR,12bR)-4a-[[(E)-3-(4-chlorophenyl)prop-2-enoyl]amino]-3-(cyclopropylmethyl)-7-oxo-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-9-yl]oxy]acetate
CFAMM00259055 CHEMBL277530 Bioactive N-[(4R,4aS,7aR,12bR)-3-(cyclopropylmethyl)-9-methoxy-7-oxo-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl]-2-(4-chlorophenyl)acetamide
CFAMM00259068 CHEMBL216365 Bioactive (E)-N-[(4R,4aS,7aR,12bR)-3-(cyclopropylmethyl)-9-methoxy-7-oxo-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl]-4-(4-chlorophenyl)but-3-enamide
CFAMM00259109 CHEMBL386492 Bioactive clocinnamox
CFAMM00259075 CHEMBL610284 Bioactive (E)-N-[(4R,12bR)-3-(cyclopropylmethyl)-9-hydroxy-7-oxo-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl]-3-(4-chlorophenyl)prop-2-enamide
CFAMM00259089 CHEMBL217395 Bioactive N-[(4R,4aS,7aR,12bR)-3-(cyclopropylmethyl)-9-methoxy-7-oxo-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl]-3-(4-chlorophenyl)propanamide
CFAMM00259082 CHEMBL607069 Bioactive (E)-N-[(4R,4aS,7aR,12bR)-9-methoxy-3-methyl-7-oxo-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl]-3-(4-chlorophenyl)prop-2-enamide
CFAMM00259074 CHEMBL607016 Bioactive (E)-N-[(4R,4aS,7aR,12bR)-9-methoxy-3-methyl-7-oxo-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl]-3-(2-chlorophenyl)prop-2-enamide
CFAMM00259101 CHEMBL610029 Bioactive (E)-N-[(4R,12bR)-3-(cyclopropylmethyl)-9-methoxy-7-oxo-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl]-3-(4-chlorophenyl)prop-2-enamide
CFAMM00259053 CHEMBL217479 Bioactive N-[(4R,4aS,7aR,12bR)-3-(cyclopropylmethyl)-9-hydroxy-7-oxo-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl]-4-(4-chlorophenyl)butanamide
CFAMM00259066 CHEMBL607125 Bioactive (E)-N-[(4R,4aS,7aR,12bR)-9-hydroxy-3-methyl-7-oxo-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl]-3-(2-methylphenyl)prop-2-enamide
CFAMM00259100 CHEMBL610028 Bioactive (E)-N-[(4R,4aS,7aR,12bR)-3-(cyclopropylmethyl)-7-oxo-9-prop-2-ynoxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl]-3-(4-chlorophenyl)prop-2-enamide
CFAMM00259113 CHEMBL383896 Bioactive (4R,4aS,7aR,12bR)-4a-[[(E)-4-(4-chlorophenyl)but-3-enyl]amino]-3-(cyclopropylmethyl)-9-hydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one
CFAMM00259052 CHEMBL217102 Bioactive (4R,4aS,7aR,12bR)-4a-[4-(4-chlorophenyl)butylamino]-3-(cyclopropylmethyl)-9-hydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one
CFAMM00259065 CHEMBL217790 Bioactive (E)-N-[(4R,4aS,7aR,12bR)-3-(cyclopropylmethyl)-9-methoxy-7-oxo-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl]-4-(4-chlorophenyl)but-2-enamide
CFAMM00259080 CHEMBL216251 Bioactive (4R,4aS,7aR,12bR)-4a-[[(E)-3-(4-chlorophenyl)prop-2-enyl]amino]-3-(cyclopropylmethyl)-9-methoxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one
CFAMM00259058 CHEMBL384118 Bioactive (4R,4aS,7aR,12bR)-4a-[[(E)-4-(4-chlorophenyl)but-2-enyl]amino]-3-(cyclopropylmethyl)-9-methoxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one
CFAMM00259106 CHEMBL448428 Bioactive N-[(4R,4aS,7aR,12bR)-3-(cyclopropylmethyl)-9-hydroxy-7-oxo-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl]-2-(4-chlorophenyl)acetamide
CFAMM00259086 CHEMBL217710 Bioactive (E)-N-[(4R,4aS,7aR,12bR)-3-(cyclopropylmethyl)-9-hydroxy-7-oxo-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl]-4-(4-chlorophenyl)but-3-enamide
CFAMM00259051 CHEMBL578422 Bioactive N-[(4R,4aS,7aR,12bR)-3-(cyclopropylmethyl)-9-methoxy-7-oxo-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl]-3-(4-chlorophenyl)prop-2-ynamide
CFAMM00259079 CHEMBL216558 Bioactive (4R,4aS,7aR,12bR)-4a-[[(E)-4-(4-chlorophenyl)but-2-enyl]amino]-3-(cyclopropylmethyl)-9-hydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one
CFAMM00259092 CHEMBL217658 Bioactive (4R,4aS,7aR,12bR)-4a-[2-(4-chlorophenyl)ethylamino]-3-(cyclopropylmethyl)-9-hydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one
CFAMM00259085 CHEMBL443311 Bioactive (4R,4aS,7aR,12bR)-4a-[3-(4-chlorophenyl)propylamino]-3-(cyclopropylmethyl)-9-hydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one
CFAMM00259063 CHEMBL610544 Bioactive (E)-N-[(4R,4aS,7aR,12bR)-3-(cyclopropylmethyl)-7-oxo-9-prop-2-enoxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl]-3-(4-chlorophenyl)prop-2-enamide
CFAMM00259077 CHEMBL610287 Bioactive (E)-N-[(4R,4aS,7aR,12bR)-9-(cyclopropylmethoxy)-3-(cyclopropylmethyl)-7-oxo-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl]-3-(4-chlorophenyl)prop-2-enamide
CFAMM00259050 CHEMBL263482 Bioactive N-[(4R,4aS,7aR,12bR)-3-(cyclopropylmethyl)-9-methoxy-7-oxo-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl]-4-(4-chlorophenyl)butanamide
CFAMM00259091 CHEMBL574175 Bioactive (4R,4aS,7aR,12bR)-4a-[3-(4-chlorophenyl)prop-2-ynylamino]-3-(cyclopropylmethyl)-9-hydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one
CFAMM00259104 CHEMBL267027 Bioactive N-[(4R,4aS,7aR,12bR)-3-(cyclopropylmethyl)-9-hydroxy-7-oxo-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl]-3-(4-chlorophenyl)propanamide
CFAMM00259097 DNC006776 Investigative Drug clocinnamox
CFAMM00259096 DNC006775 Investigative Drug MC-CAM

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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