CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2080
Family Name 5-hydroxytryptamine receptor 6 Ligand 4-(4-benzenesulfonamidophenyl)piperazine Family
No. of Seeds 4 No. of Other Members 5
Family Centroid CFAMM00259130 Functional Category Investigative Drug
Superfamily Mannose-6-phosphate isomerase Inhibitor Sulfanilamide Superfamily
Class Class 597

Cousin Family NamesSeedsMembers
Calmodulin inhibitor phenothiazine derivative Trifluoperazine ... 3 30
D(2) dopamine receptor Ligand phenothiazine analog Prochlorper... 4 25
Alpha adrenergic receptor ligand phenothiazine derivative Thio... 4 10
Muscarinic acetylcholine receptor M5 ligand phenothiazine deri... 8 37
Dihydropterin pyrophosphokinase-dihydropteroate synthase Inhib... 9 88
Histamine H1 receptor ligand phenothiazine derivative Mequitaz... 3 2
Mannose-6-phosphate isomerase Inhibitor Sulfacetamide Family 19 117
Mannose-6-phosphate isomerase Inhibitor Sulfoxone Family 3 20
Mannose-6-phosphate isomerase Inhibitor Sulfanilamide Family 4 8
5-hydroxytryptamine receptor Ligand Lu AA21004 Family 13 39
5-hydroxytryptamine receptor 1A and Sigma non-opioid intracell... 7 28
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 2-morp... 6 81
Carbonic anhydrase 2 and Prostaglandin G/H synthase 2 Inhibito... 1 1
5-hydroxytryptamine receptor 2A Ligand Cinanserin Family 3 27
Fructose-1,6-bisphosphatase 1 Inhibitor 1-(4-aminophenylsulfon... 2 1
Carbonic anhydrase 2 and Carbonic anhydrase 9 Inhibitor 3-((4-... 5 4
Carbonic anhydrase 9 and Carbonic anhydrase 12 Inhibitor Sodiu... 2 11
D(2) dopamine receptor Ligand 1-benzyl-4-[3-(methylsulfonyl)ph... 2 7
Cholinesterase Inhibitor N-cyclohexyl-1'h-phenothiazine-1'-car... 7 2
Cholinesterase Inhibitor N-p-tolyl-1'h-phenothiazine-1'-carbox... 4 1
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Thiour... 3 14
Sodium-dependent serotonin transporter and Sodium-dependent no... 6 1
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor 2-amin... 2 2
5-hydroxytryptamine receptor 6 and 5-hydroxytryptamine recepto... 9 26
Carbonic anhydrase 2 and Carbonic anhydrase 1 inhibitor 2-[car... 3 3
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 18 12
Sodium-dependent serotonin transporter and Transporter inhibit... 4 0
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor AGN-PC... 6 2
D(4) dopamine receptor and 5-hydroxytryptamine receptor 2A lig... 1 3
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 1
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-[[4... 7 11
Growth hormone secretagogue receptor type 1 ligand SureCN47963... 3 3
Growth hormone secretagogue receptor type 1 ligand SureCN48016... 5 4
D(3) dopamine receptor and D(2) dopamine receptor ligand 4-met... 2 0
Sigma non-opioid intracellular receptor 1 ligand 3-[4-(azepan-... 8 1
Carbonic anhydrase 12 and Carbonic anhydrase 9 inhibitor ST510... 7 3
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 2
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 2 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 0
5-hydroxytryptamine receptor 1A ligand AGN-PC-00JBJI family 1 1
Protein-glutamine gamma-glutamyltransferase 2 and Coagulation ... 3 2
Coagulation factor XIII A chain and Protein-glutamine gamma-gl... 2 3
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor 1,2,3,... 1 0
5-hydroxytryptamine receptor 6 ligand 4-amino-N-[3-bromo-5-(me... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00259128 DNC006784 Investigative Drug 4-(3-benzenesulfonamidophenyl)piperazine
CFAMM00259131 DNC006782 Investigative Drug 4-(3-benzenesulfonylphenyl)piperazine
CFAMM00259130 DNC006783 Investigative Drug 4-(4-benzenesulfonamidophenyl)piperazine
CFAMM00259129 DNC006780 Investigative Drug 4-(2-benzenesulfonylphenyl)piperazine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

22932 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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