CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2081
Family Name 5-hydroxytryptamine receptor 6 Ligand 2-(3-benzenesulfonyl)phenyl-1-aminoethane Family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00259145 Functional Category Investigative Drug
Superfamily 5-hydroxytryptamine receptor 6 Ligand 2-(3-benzenesulfonyl)phenyl-1-aminoethane Superfamily
Class Class 1448

Cousin Family NamesSeedsMembers
Alpha-1B adrenergic receptor ligand phenethylamine derivative ... 12 283
Nuclear factor NF-kappa-B p100 subunit Inhibitor BAY11-7082 Fa... 2 17
Carbonic anhydrase 2 Inhibitor 4-(2-aminoethyl)benzenesulfonam... 3 30
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand SCH-3... 17 21
5-hydroxytryptamine receptor 6 Ligand N-(3-(2-aminoethyl)pheny... 8 25
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 15 11
5-hydroxytryptamine receptor 6 ligand [(1R)-6-(3-fluorophenyl)... 6 6
5-hydroxytryptamine receptor 6 ligand (1R)-1-[(dimethylsulfamo... 10 4
5-hydroxytryptamine receptor 6 and Cytochrome P450 2D6 ligand ... 2 0
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor 4-[2-(... 1 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 1


External ID

Functional Category

Molecule Name

CFAMM00259145 DNC006788 Investigative Drug 2-(3-benzenesulfonyl)phenyl-1-aminoethane
CFAMM00259142 DNC006787 Investigative Drug 2-(3-phenylthio)phenyl)-1-aminoethane
CFAMM00259141 DNC006785 Investigative Drug 2-(4-(benzenesulfonyl)phenyl)-1-aminoethane

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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