CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2082
Family Name 5-hydroxytryptamine receptor 6 Ligand N-(3-(2-aminoethyl)phenyl)benzenesulfonamide Family
No. of Seeds 8 No. of Other Members 25
Family Centroid CFAMM00259187 Functional Category Investigative Drug
Superfamily 5-hydroxytryptamine receptor 6 Ligand N-(3-(2-aminoethyl)phenyl)benzenesulfonamide Superfamily
Class Class 2249

Cousin Family NamesSeedsMembers
Dihydropterin pyrophosphokinase-dihydropteroate synthase Inhib... 9 88
Mannose-6-phosphate isomerase Inhibitor Sulfacetamide Family 19 117
5-hydroxytryptamine receptor 1A and Sigma non-opioid intracell... 7 28
Beta-lactamase Inhibitor M-aminophenylboronic Acid Family 2 16
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor N-(4-s... 12 92
Carbonic anhydrase 2 Inhibitor 4-(2-aminoethyl)benzenesulfonam... 3 30
5-hydroxytryptamine receptor 6 Ligand 4-(1h-inden-1-ylmethyl)-... 5 99
Potassium voltage-gated channel subfamily A member 5 Ligand N-... 8 32
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-hydr... 3 3
Reverse transcriptase Inhibitor 2-amino-6-(naphthalene-1-sulfo... 3 6
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 2-morp... 6 81
Alpha-2A adrenergic receptor Ligand SK&F-29661 Family 3 42
Carbonic anhydrase 2 Inhibitor 3-nitro-benzenesulfonamide Family 3 19
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-isot... 1 2
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor N-[4-(... 2 12
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-[2-(... 5 72
Aromatase Inhibitor 3-amino-4'-amino-trans-stilbene Family 5 47
5-hydroxytryptamine receptor 6 Ligand 2-(3-benzenesulfonyl)phe... 3 4
Kinesin-like protein KIF11 Inhibitor N-(4'-chloro-4-biphenylyl... 1 2
Kinesin-like protein KIF11 Inhibitor N-[4'-(trifluoromethyl)-4... 3 13
Carbonic anhydrase 2 and Prostaglandin G/H synthase 2 Inhibito... 8 10
Carbonic anhydrase 2 Inhibitor 4-((benzylideneamino)methyl)ben... 2 1
Carbonic anhydrase 2 and Carbonic anhydrase 9 Inhibitor 3-((4-... 5 4
Reverse transcriptase Inhibitor 2-amino-6-(2-cyano-benzenesulf... 16 2
Prostaglandin G/H synthase 1 Inhibitor 4-amino-n-(2-chlorophen... 2 3
Carbonic anhydrase Inhibitor 4-amino-3-fluoro-5-iodobenzenesul... 1 0
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Thiour... 3 14
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 8 10
Thyroid hormone receptor beta and Beta-lactamase ligand CHEMBL... 1 3
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor AGN-PC... 6 2
Bifunctional epoxide hydrolase 2 inhibitor 1-(2,4-dimethylphen... 4 8
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-[[4... 7 11
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor 4-[2-(... 1 0
Carbonic anhydrase 1 and Carbonic anhydrase 13 inhibitor 4-(be... 1 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 2
Sodium-dependent serotonin transporter and Sodium-dependent no... 4 1
5-hydroxytryptamine receptor 6 ligand AGN-PC-014RDG family 1 3
Prelamin-A/C and Muscarinic acetylcholine receptor M1 ligand B... 1 3
Carbonic anhydrase and Carbonic anhydrase 2 inhibitor AGN-PC-0... 2 0
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor 1,2,3,... 1 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 3 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00259163 DNC006793 Investigative Drug N-phenyl-3-(2-aminoethyl)benzenesulfonamide
CFAMM00259162 DNC009157 Investigative Drug 4-amino-N-(4-sulfamoylbenzyl)benzenesulfonamide
CFAMM00259187 DNC006789 Investigative Drug N-(3-(2-aminoethyl)phenyl)benzenesulfonamide
CFAMM00259184 DNC006786 Investigative Drug N-(4-(2-aminoethyl)phenyl)benzenesulfonamide
CFAMM00259151 DNC013254 Investigative Drug 4-amino-N-p-tolylbenzenesulfonamide
CFAMM00259165 DNC006791 Investigative Drug N-(3-(aminomethyl)phenyl)benzenesulfonamide
CFAMM00259164 DNC006790 Investigative Drug N-(3-(3-aminopropyl)phenyl)benzenesulfonamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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