CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2084
Family Name Fatty acid-binding protein, adipocyte and Fatty acid-binding protein, epidermal Inhibitor 2-(2,3-bis(2-chlorobenzyloxy)phenyl)acetic Acid Family
No. of Seeds 4 No. of Other Members 102
Family Centroid CFAMM00259287 Functional Category Investigative Drug with Natural Product
Superfamily Fatty acid-binding protein, adipocyte and Fatty acid-binding protein, epidermal Inhibitor 2-(2,3-bis(2-chlorobenzyloxy)phenyl)acetic Acid Superfamily
Class Class 864

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Fenoprofen Family 4 1077
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Aldehyde oxidase Inhibitor Isovanillin Family 6 429
Ipriflavone family 62 2480
Rotenone family 16 107
Endothelin-1 receptor Ligand PD156707 Family 41 211
Peroxisome proliferator-activated receptor gamma Ligand (2s)-2... 2 14
cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor 2,5-... 2 96
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Ellagi... 1 11
Aromatase Inhibitor 3,4-bis(3,4-dimethoxyphenyl)furan-2(5h)-on... 4 86
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 3 0
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
Liver carboxylesterase 1 Inhibitor 2-methoxy-3,4-methylenediox... 4 26
Cocaine esterase and Liver carboxylesterase 1 inhibitor 2-Chlo... 1 5
Endothelin-1 receptor ligand SureCN8117947 family 1 3
Peroxisome proliferator-activated receptor delta and Peroxisom... 4 2
Transthyretin inhibitor AGN-PC-046XQV family 1 6
Endothelin-1 receptor and Endothelin B receptor ligand SureCN8... 3 1
Cysteinyl leukotriene receptor 1 ligand 4-[(E)-3-[4-[4-(4-chlo... 1 0
Amine oxidase [flavin-containing] B and Amine oxidase [flavin-... 1 10
Phenylacetic Acid Derivatives Metabolite Guaicyl phenylacetate... 1 3
NP 3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-6-ethyl-4-oxo-4h-ch... 33 4
NP (z)-6-((4-bromobenzyl)oxy)-2-(3,4-dimethoxybenzylidene)benz... 13 2
bromobenzoate NP ZINC09346025 Family 20 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00259378 CHEMBL437489 Bioactive AGN-PC-03MXPD
CFAMM00259295 CHEMBL378181 Bioactive AGN-PC-03MXPI
CFAMM00259287 DNC006795 Investigative Drug 2-(2,3-bis(2-chlorobenzyloxy)phenyl)acetic acid
CFAMM00259286 DNC006796 Investigative Drug BMS-480404

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27526 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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