CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2085
Family Name Serine/threonine-protein kinase Chk1 and Wee1-like protein kinase Inhibitor 9-hydroxypyrrolo[3,4-c]carbazole-1,3(2h,6h)-dione Family
No. of Seeds 2 No. of Other Members 101
Family Centroid CFAMM00259399 Functional Category Investigative Drug
Superfamily Wee1-like protein kinase and Serine/threonine-protein kinase Chk1 Binder Superfamily
Class Class 2321

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A Ligand Melatonin Family 20 988
DNA Binder Elliptinium Acetate Family 11 116
Indeglitazar family 3 39
5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 11 41
DNA topoisomerase 1 Inhibitor KT6006 Family 3 53
Cyclin-dependent kinase 1 and Cyclin-dependent kinase 2 Inhibi... 1 8
AP endonuclease APE1 Inhibitor 5-fluoro-1h-indole-2-carboxylic... 2 61
Vascular endothelial growth factor receptor 2 Ligand Isoindoli... 11 36
Serine/threonine-protein kinase Chk1 Inhibitor A-432411 Family 4 70
Platelet-derived growth factor receptor alpha and Platelet-der... 4 54
Tyrosine-protein phosphatase non-receptor type 1 Ligand Cauler... 2 8
Acetylcholinesterase and Cholinesterase Inhibitor 6-hydroxy-1,... 4 2
High affinity nerve growth factor receptor and Mitogen-activat... 2 7
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-366... 5 75
Kinesin-like protein KIF11 Inhibitor Methyl 7-tert-butyl-9h-ca... 2 9
Arachidonate 5-lipoxygenase Inhibitor TZI-41127 Family 7 34
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 3 16
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 4 41
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 3 5
Renin inhibitor SureCN1144364 family 3 15
Histamine H3 receptor ligand AGN-PC-00BG7Z family 11 49
Poly [ADP-ribose] polymerase 1 inhibitor SureCN5002485 family 2 11
Protein kinase C alpha type and Protein kinase C delta type in... 4 37
Acetylcholinesterase inhibitor CHEMBL1651140 family 4 4
NS5B protein inhibitor AGN-PC-00A17Z family 1 23
Translocator protein inhibitor (4S)-N,N-diethyl-9-(2-fluoranyl... 9 10
RAC-beta serine/threonine-protein kinase and 3-phosphoinositid... 1 1
Seprase and Prolyl endopeptidase inhibitor N-[2-[(2S)-2-cyanop... 1 3
Proto-oncogene tyrosine-protein kinase receptor Ret and Vascul... 5 14
Leucine-rich repeat serine/threonine-protein kinase 2 and Vasc... 1 1
Serine/threonine-protein kinase PLK4 inhibitor (3E)-5-methoxy-... 4 0
Wee1-like protein kinase and Serine/threonine-protein kinase C... 3 51
Serine/threonine-protein kinase Chk1 and Wee1-like protein kin... 3 12
Wee1-like protein kinase and Serine/threonine-protein kinase C... 8 0
Gonadotropin-releasing hormone receptor ligand SureCN7905635 f... 2 2
Histone deacetylase 3 and Histone deacetylase 9 inhibitor AGN-... 4 20
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 6 8
Signal transducer and activator of transcription 1-alpha/beta ... 1 36
Microtubule-associated protein tau and Glycogen synthase kinas... 9 15
Arachidonate 5-lipoxygenase inhibitor AGN-PC-071TED family 9 12
Vascular endothelial growth factor receptor 2 ligand SureCN235... 1 1
Indoles Metabolite Mukeic acid Family 1 1
2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-2-ium-8-carboxylate N... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00259399 DNC006798 Investigative Drug 9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione
CFAMM00259464 DNC007765 Investigative Drug SU-6689

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

46110 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543