CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2088
Family Name Coagulation factor X and Prothrombin Inhibitor BMS-740808 Family
No. of Seeds 64 No. of Other Members 8
Family Centroid CFAMM00259540 Functional Category Investigative Drug
Superfamily Coagulation factor X and Prothrombin Inhibitor BMS-740808 Superfamily
Class Class 2345

Cousin Family NamesSeedsMembers
Coagulation factor X Inhibitor Apixaban Family 34 52
Coagulation factor IX and Coagulation factor X Inhibitor Razax... 22 34
Coagulation factor X and Prothrombin inhibitor 1-(3-amino-1,2-... 4 0
Coagulation factor X and Prothrombin inhibitor 2-(3-amino-1,2-... 5 3
Coagulation factor X inhibitor AGN-PC-046RMH family 5 0
Coagulation factor X and Prothrombin inhibitor 6-[4-[2-[[(3R)-... 15 2
Coagulation factor X inhibitor 1-(4-methoxyphenyl)-7-oxo-6-[4-... 5 0
Coagulation factor X and Prothrombin inhibitor 1-(4-methoxyphe... 8 0
Coagulation factor X and Prothrombin inhibitor 1-(3-amino-1,2-... 9 0
Coagulation factor X inhibitor 1-(3-amino-1,2-benzoxazol-5-yl)... 3 0
Coagulation factor X inhibitor SureCN5107814 family 6 0
Coagulation factor X inhibitor SureCN6603523 family 4 0
Coagulation factor X inhibitor 1-[2-(3-amino-1,2-benzoxazol-5-... 7 0
Coagulation factor X inhibitor AGN-PC-02YW2V family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00259547 CHEMBL205288 Bioactive Aminobenzisoxazole 2n
CFAMM00259513 CHEMBL210175 Bioactive 1-(3-amino-1,2-benzoxazol-5-yl)-7-[4-[2-[(dimethylamino)methyl]phenyl]phenyl]-3-(trifluoromethyl)-5,6-dihydro-4H-pyrazolo[3,4-c]azepin-8-one
CFAMM00259527 CHEMBL250349 Bioactive 1-(3-amino-1,2-benzoxazol-5-yl)-5-[5-[2-[(dimethylamino)methyl]phenyl]-2,3-dihydroindole-1-carbonyl]pyrazole-3-carboxamide
CFAMM00259553 CHEMBL380617 Bioactive Aminobenzisoxazole 2e
CFAMM00259506 CHEMBL246738 Bioactive AGN-PC-046RME
CFAMM00259520 CHEMBL373528 Bioactive 1-(3-amino-1,2-benzoxazol-4-yl)-6-[4-[2-[(dimethylamino)methyl]phenyl]phenyl]-3-(trifluoromethyl)-4,5-dihydropyrazolo[3,4-c]pyridin-7-one
CFAMM00259533 CHEMBL399332 Bioactive 1-(3-amino-1,2-benzoxazol-5-yl)-5-[5-[2-(pyrrolidin-1-ylmethyl)phenyl]-2,3-dihydroindole-1-carbonyl]pyrazole-3-carboxamide
CFAMM00259546 CHEMBL209483 Bioactive AGN-PC-02YW2P
CFAMM00259559 CHEMBL382339 Bioactive Aminobenzisoxazole 2j
CFAMM00259526 CHEMBL204416 Bioactive Aminobenzisoxazole 2o
CFAMM00259512 CHEMBL250560 Bioactive SureCN1999516
CFAMM00259539 CHEMBL214444 Bioactive 1-(3-amino-1,2-benzoxazol-5-yl)-6-[4-[2-[[(3S)-3-hydroxypyrrolidin-1-yl]methyl]phenyl]phenyl]-3-methylpyrazolo[4,3-d]pyrimidin-7-one
CFAMM00259552 CHEMBL380618 Bioactive Aminobenzisoxazole 2f
CFAMM00259532 CHEMBL399331 Bioactive SureCN6604148
CFAMM00259545 CHEMBL378222 Bioactive SureCN8360892
CFAMM00259511 CHEMBL263252 Bioactive Aminobenzisoxazole 2t
CFAMM00259525 CHEMBL214462 Bioactive 1-(3-amino-1,2-benzoxazol-5-yl)-6-[4-[2-[[(3R)-3-hydroxypyrrolidin-1-yl]methyl]phenyl]phenyl]-3-(trifluoromethyl)-4H-pyrazolo[4,3-d]pyrimidine-5,7-dione
CFAMM00259538 CHEMBL402166 Bioactive 1-[4-[2-[2-(3-amino-1,2-benzoxazol-5-yl)-5-(trifluoromethyl)pyrazol-3-yl]-2-oxoethyl]phenyl]piperidin-2-one
CFAMM00259504 CHEMBL209916 Bioactive 1-(3-amino-1,2-benzoxazol-5-yl)-7-[4-[2-[(dimethylamino)methyl]phenyl]-2-fluorophenyl]-3-(trifluoromethyl)-5,6-dihydro-4H-pyrazolo[3,4-c]azepin-8-one
CFAMM00259517 CHEMBL214550 Bioactive AGN-PC-03K47M
CFAMM00259531 CHEMBL385487 Bioactive 1-(3-amino-1,2-benzoxazol-5-yl)-6-[4-[2-[[(3R)-3-hydroxypyrrolidin-1-yl]methyl]phenyl]phenyl]-5-methyl-3-(trifluoromethyl)pyrazolo[4,3-d]pyrimidin-7-one
CFAMM00259544 CHEMBL377589 Bioactive AGN-PC-02YW2O
CFAMM00259557 CHEMBL380356 Bioactive Aminobenzisoxazole 2c
CFAMM00259510 CHEMBL263767 Bioactive BMS-740808 Analogue 7c
CFAMM00259524 CHEMBL426313 Bioactive Aminobenzisoxazole 2h
CFAMM00259537 CHEMBL381316 Bioactive Aminobenzisoxazole 2a
CFAMM00259503 CHEMBL205187 Bioactive Aminobenzisoxazole 2d
CFAMM00259516 CHEMBL212770 Bioactive AGN-PC-03K47A
CFAMM00259530 CHEMBL205383 Bioactive Aminobenzisoxazole 2v
CFAMM00259543 CHEMBL402881 Bioactive AGN-PC-046QCI
CFAMM00259509 CHEMBL379397 Bioactive 1-(3-amino-1,2-benzoxazol-5-yl)-6-[2-fluoro-4-[2-[[(3R)-3-hydroxypyrrolidin-1-yl]methyl]phenyl]phenyl]-3-methyl-4,5-dihydropyrazolo[3,4-c]pyridin-7-one
CFAMM00259523 CHEMBL205653 Bioactive Aminobenzisoxazole 2q
CFAMM00259536 CHEMBL380430 Bioactive Aminobenzisoxazole 2m
CFAMM00259549 CHEMBL381836 Bioactive Aminobenzisoxazole 2l
CFAMM00259502 CHEMBL386463 Bioactive 1-(3-amino-1,2-benzoxazol-5-yl)-6-[4-[2-[[(3R)-3-hydroxypyrrolidin-1-yl]methyl]phenyl]phenyl]-3,5-dimethylpyrazolo[4,3-d]pyrimidin-7-one
CFAMM00259515 CHEMBL265087 Bioactive AGN-PC-046QCH
CFAMM00259529 CHEMBL359695 Bioactive 2-(3-amino-1,2-benzoxazol-5-yl)-N-[2-fluoro-4-(pyrrolidine-1-carbonyl)phenyl]-5-(trifluoromethyl)pyrazole-3-carboxamide
CFAMM00259555 CHEMBL204994 Bioactive Aminobenzisoxazole 2b
CFAMM00259508 CHEMBL428982 Bioactive AGN-PC-03K47G
CFAMM00259522 CHEMBL385679 Bioactive 1-(3-amino-1,2-benzoxazol-5-yl)-6-[4-[2-[(dimethylamino)methyl]phenyl]phenyl]-3-methyl-4,5-dihydropyrazolo[3,4-c]pyridin-7-one
CFAMM00259535 CHEMBL380431 Bioactive Aminobenzisoxazole 2u
CFAMM00259548 CHEMBL213888 Bioactive AGN-PC-046QCF
CFAMM00259501 CHEMBL215158 Bioactive 1-(3-amino-1,2-benzoxazol-5-yl)-6-[4-[2-[(4-hydroxypiperidin-1-yl)methyl]phenyl]phenyl]-3-(trifluoromethyl)-4H-pyrazolo[4,3-d]pyrimidine-5,7-dione
CFAMM00259528 CHEMBL395823 Bioactive 2-(3-amino-1,2-benzoxazol-5-yl)-N-[1-[2-[[(2R)-2-hydroxypyrrolidin-1-yl]methyl]phenyl]piperidin-4-yl]-5-(trifluoromethyl)pyrazole-3-carboxamide
CFAMM00259541 CHEMBL215426 Bioactive 1-(3-amino-1,2-benzoxazol-5-yl)-6-[4-[2-[(dimethylamino)methyl]phenyl]phenyl]-3-(trifluoromethyl)pyrazolo[4,3-d]pyrimidin-7-one
CFAMM00259554 CHEMBL254831 Bioactive SureCN5107480
CFAMM00259507 CHEMBL407942 Bioactive Aminobenzisoxazole 2p
CFAMM00259521 CHEMBL380405 Bioactive 1-(3-amino-1,2-benzoxazol-5-yl)-6-[4-[2-[[(3R)-3-hydroxypyrrolidin-1-yl]methyl]phenyl]phenyl]-3-methyl-4,5-dihydropyrazolo[3,4-c]pyridin-7-one
CFAMM00259534 CHEMBL380829 Bioactive Aminobenzisoxazole 2r
CFAMM00259540 DNC006811 Investigative Drug BMS-740808

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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