CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2089
Family Name Carbonic anhydrase 2 and Carbonic anhydrase 4 Inhibitor 1-(3,4-dichlorophenyl)-3-hydroxyurea Family
No. of Seeds 2 No. of Other Members 9
Family Centroid CFAMM00259560 Functional Category Investigative Drug
Superfamily Carbonic anhydrase 2 and Carbonic anhydrase 4 Inhibitor 1-(3,4-dichlorophenyl)-3-hydroxyurea Superfamily
Class Class 1917

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Proguanil Family 8 46
Bifunctional epoxide hydrolase 2 Inhibitor 1-cyclohexyl-3-phen... 5 65
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-chloro-phenyl)... 5 50
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
DNA topoisomerase Inhibitor 6-(3-iodo-phenylamino)-1h-pyrimidi... 2 5
D(3) dopamine receptor and D(2) dopamine receptor ligand 3-[4-... 4 23
Inosine-5'-monophosphate dehydrogenase inhibitor 1-(3,4-dichlo... 1 1
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor 1-(4-c... 1 0
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 1 0
Bloom syndrome protein and Prelamin-A/C inhibitor DCEBIO family 1 1


External ID

Functional Category

Molecule Name

CFAMM00259573 DNC008488 Investigative Drug 1-(3,4-dichlorophenyl)-3-(3,5-dichlorophenyl)urea
CFAMM00259560 DNC006812 Investigative Drug 1-(3,4-dichlorophenyl)-3-hydroxyurea

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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