CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2108
Family Name 5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine receptor 1D Ligand Brolamfetamine Family
No. of Seeds 11 No. of Other Members 21
Family Centroid CFAMM00260058 Functional Category Investigative Drug
Superfamily 5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine receptor 1A Binder Superfamily
Class Class 2354

Cousin Family NamesSeedsMembers
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Alpha adrenergic receptor ligand catecholamine Phenylephrine F... 4 39
Alpha-1 adrenergic receptor ligand Dextroamphetamine derivativ... 5 29
Sodium channel protein type 5 subunit alpha Ligand Mexiletine ... 7 74
Alpha-1B adrenergic receptor ligand Phenylephrine analog Metho... 9 56
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 5 11
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
5-hydroxytryptamine receptor 2A Ligand C-(5-bromo-4,7-dimethox... 9 6
Histamine H3 receptor Ligand (r)-1-(2-methoxyphenethyl)-2-meth... 10 27
Sodium-dependent dopamine transporter and Sodium-dependent nor... 9 16
5-hydroxytryptamine receptor 1A Ligand 9-methoxy-1,2,3,4-tetra... 7 10
5-hydroxytryptamine receptor 2A Ligand C-(9h-xanthen-9-yl)-met... 3 5
5-hydroxytryptamine receptor 2A Ligand 1-(2,6-dimethoxy-4-meth... 14 3
5-hydroxytryptamine receptor 2A ligand 1-(4-bromo-3,6,7,8-tetr... 11 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 4 2
Melatonin receptor type 1A and Melatonin receptor type 1C liga... 1 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 2 0


External ID

Functional Category

Molecule Name

CFAMM00260070 CHEMBL365958 Bioactive (1R,2R)-1-(4-bromo-2,5-dimethoxyphenyl)-1-methoxypropan-2-amine
CFAMM00260063 CHEMBL191420 Bioactive (1S,2S)-1-(4-bromo-2,5-dimethoxyphenyl)-1-methoxypropan-2-amine
CFAMM00260069 CHEMBL365711 Bioactive AGN-PC-0A4Q7K
CFAMM00260052 CHEMBL351858 Bioactive Methyl-DOB
CFAMM00260078 CHEMBL364718 Bioactive (1S,2R)-1-(4-bromo-2,5-dimethoxyphenyl)-1-methoxypropan-2-amine
CFAMM00260049 CHEMBL69700 Bioactive SureCN1048339
CFAMM00260065 DNC006863 Investigative Drug 2,5-dimethoxy-4-bromophenethylamine
CFAMM00260046 DNC012401 Investigative Drug 2-(2-Amino-propyl)-5-bromo-4-methoxy-phenol
CFAMM00260044 DNC012392 Investigative Drug 2-(4-Bromo-2-methoxy-phenyl)-1-methyl-ethylamine
CFAMM00260058 DNC011760 Investigative Drug Brolamfetamine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



88578 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543