CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFID2109
Family Name 5-hydroxytryptamine receptor 2A Ligand C-(5-bromo-4,7-dimethoxyindan-1-yl)methylamine Family
No. of Seeds 9 No. of Other Members 6
Family Centroid CFAMM00260085 Functional Category Investigative Drug
Superfamily 5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine receptor 1A Binder Superfamily
Class Class 2354

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Mexiletine ... 7 74
Alpha-1B adrenergic receptor ligand Phenylephrine analog Metho... 9 56
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 11 21
5-hydroxytryptamine receptor 2A Ligand 1-(2,6-dimethoxy-4-meth... 14 3
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 1 2
5-hydroxytryptamine receptor 2A ligand 1-(4-bromo-3,6,7,8-tetr... 11 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 4 2
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 6 3
5-hydroxytryptamine receptor 2A ligand (1S,2R)-2-amino-1-(4-br... 2 0
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 2 0


External ID

Functional Category

Molecule Name

CFAMM00260087 CHEMBL379637 Bioactive [(7R)-3-bromo-2,5-dimethoxy-7-bicyclo[4.2.0]octa-1(6),2,4-trienyl]methanamine
CFAMM00260086 CHEMBL94982 Bioactive SureCN6361976
CFAMM00260079 CHEMBL445106 Bioactive CHEMBL445106
CFAMM00260092 CHEMBL212197 Bioactive TCB-2
CFAMM00260091 CHEMBL191051 Bioactive BOB (psychedelic)
CFAMM00260090 CHEMBL331864 Bioactive CHEMBL331864
CFAMM00260083 CHEMBL119323 Bioactive CHEMBL119323
CFAMM00260085 DNC006864 Investigative Drug C-(5-bromo-4,7-dimethoxyindan-1-yl)methylamine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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